Norkolut for early pregnancy termination

Norkolut for endometriosis is prescribed to women with grades 1 and 2 of the hormone-dependent disease. It is also actively used to consolidate the result after surgical removal of lesions and endometriomas (ovarian cysts caused by endometriosis). The medication is prescribed for diseases of the female reproductive system that are hormonally dependent and allows you to get rid of disturbing symptoms in a short time. The effectiveness of treatment with Norkolut is assessed after several months of regular use. The results obtained set the vector for further actions for the doctor.

Is Norkolut a hormonal drug or not?

Norkolut's composition contains the progestogen component norethisterone, which transforms the uterine mucosa from the proliferation phase to the secretory phase. This leads to blocking the secretion of gonadotropin by the pituitary gland, preventing the maturation of follicles and the onset of ovulation. The hormonal drug is well absorbed from the stomach and undergoes intensive primary metabolism by the liver and intestinal wall.

The bioavailability of the active component is 50-77%. Half an hour after taking the drug dose, it reaches maximum serum concentration. Metabolites are excreted by the kidneys and intestines in the form of conjugates with glucuronic acid. The half-life of the first phase is 2.5 hours, the final half-life is 8 hours. 80% of all metabolites are excreted by the kidneys.

Composition and release form of the drug

Norkolut is a hormonal drug. It belongs to the group of gestagens and is a synthetic analogue of the female sex hormone progesterone. It is used by gynecologists where it is necessary to change one’s own hormonal levels and achieve a decrease in estrogen levels.

The active ingredient of the drug is norethisterone. Available in white tablets with a dosage of 5 mg. One package contains 20 tablets. It is an inexpensive hormonal product - one package will cost 150-200 rubles. Dispensed in a pharmacy with a doctor's prescription.

Norkolut is an inexpensive drug (relative to the cost of other hormonal drugs).

Directions for use and dosage

The tablets are intended for oral administration. For premenstrual syndrome, mastodynia or dysmenorrhea, from days 16 to 25 of the menstrual cycle, 5-10 mg is prescribed daily along with estrogen. For uterine fibroids, from days 5 to 25 of the cycle, take 5-10 mg for a course of up to six months. To conduct a diagnostic progesterone test, it is optimal to take 10 mg for 10 days. The reaction is natural if, 3-7 days after the test, spotting appears and persists for 3-4 days.

If the pregnancy was terminated between 16 and 28 weeks of gestation, to prevent lactation, take 15 mg of the drug on the first day, 10 mg on days 2-3, and 5 mg on days 4 to 7. If the pregnancy was terminated at 28-36 weeks of gestation, 15 mg is prescribed on the first day, 10 mg on days 2-3, and 10 mg on days 4 to 7. To stop lactation, the first three days take 20 mg daily, from days 4 to 7 - 15 mg, from days 8 to 10 - 10 mg.

Norkolut to induce menstruation

If a girl or woman has a delay in menstruation, you can induce them by taking Norkolut tablets. Their constituent component is similar to the hormone gestagen, therefore it normalizes the cycle. The doctor prescribes 2 tablets every day for a week, after which you need to wait up to 5-8 days until menstruation begins. When prescribing 1-2 tablets per day, the wait will be 10 days. Such procedures cannot be performed frequently.

Norkolut for abortion

In the first days of delayed menstruation associated with possible pregnancy, you can take 2 tablets over a course of 3-5 days to induce menstruation and rejection of the fertilized egg from the uterine cavity. Such use should not be prescribed independently, only after consultation with a doctor. Such termination of pregnancy is contraindicated during puberty.

For endometrial hyperplasia

You should take Norkolut for endometrial hyperplasia according to the instructions. After confirmation of the dysfunctional nature of the bleeding by histological analysis (no more than six months before the start of treatment), take 5-10 mg daily for a course of 6-12 days. After achieving the effect, from days 16 to 25 of the cycle, take 5-10 mg daily along with estrogen to prevent relapse. A similar scheme is used for anovulatory metrorrhagia. For endometriosis, doctors prescribe 5 mg every day in a six-month course for days 5-25 of the cycle.

Norkolut for delaying menstruation

According to the instructions, Norkolut can be taken to delay the onset of menstruation. Treatment begins 8 days before the expected menstruation and continues for 12 days. Take 2 tablets a day, this is enough to delay your period by 7-8 days.

During menopause

During menopause, the female body lacks sex hormones. The active component of Norkolut replaces them, so the symptoms are reduced and the state of health is stabilized. During menopause, the medicine affects the uterine mucosa and eliminates endometrial hyperplasia. The standard dosage is one tablet per day, with a maximum of 30 mg per day. It is better to take the medicine at the same time, wash it down with water without chewing. The course of treatment lasts up to 5 months. Eating does not affect the absorption of the medicine.

NORCOLUT: instructions for use and analogues

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NORCOLUT is a progestogen. Belongs to the group of sex hormones and modulators of the reproductive system - estrene derivatives (G03DC02). Active ingredient: Norethisterone.

You need to know that the bioavailability of the drug NORCOLUT is 50-77%. The drug is prescribed with caution in combination with hypoglycemic drugs. Dispensed with a doctor's prescription!

Instructions for use of NORKOLUT

Directions for use and dosage

NORCOLUT is taken orally.

Premenstrual syndrome, mastodynia, dysmenorrhea: during the period from the 16th to the 25th day of the menstrual cycle, 5-10 mg/day NORCOLUT (1-2 tablets), can be taken together with estrogen.

Diagnostic progesterone test: the best option is to prescribe 10 mg of the drug for 10 days. The reaction is regarded as natural if moderate bleeding appeared 3-7 days after stopping the drug and persisted for 3-4 days.

Prevention of lactation: in case of termination of pregnancy between the 16th and 28th weeks, on the 1st day, take 15 mg of NORCOLUT (3 tablets), on the 2nd and 3rd days, take 10 mg/day (2 tablets). ), from the 4th to the 7th days, take 5 mg/day (1 tablet). In case of termination of pregnancy between the 28th and 36th weeks, take 15 mg (3 tablets) on the 1st day, and 10 mg/day (2 tablets) from the 2nd to 7th days.

Termination of lactation: from days 1 to 3, 20 mg/day is prescribed, from days 4 to 7 - 15 mg/day, from days 8 to 10 - 10 mg/day.

Endometriosis: from the 5th to the 25th day of the cycle, 5 mg/day for 6 months. Further treatment of endometriosis is at the discretion of the doctor.

NORCOLUT for fibroids

Prescribe tablets 5-10 mg/day from the 5th to the 25th day of the menstrual cycle for no more than 6 months.

NORCOLUT for endometrial hyperplasia

Anovulatory metrorrhagia, endometrial hyperplasia (dysfunctional bleeding must be confirmed by histological analysis no more than 6 months before treatment): 5-10 mg/day (1-2 tablets) for 6-12 days. After achieving the desired effect, between the 16th and 25th days of the cycle, 5-10 mg / day, usually together with estrogen, to prevent relapse.

NORKOLUT after 40 years

Hormonal changes occur in a woman’s body during this period. The instructions for using the drug NORCOLUT during menopause differ from the course for women of childbearing age.

Typically the duration of use is 6 months or more. Every 3 months, re-examination and dose adjustment.

For example, for uterine fibroids, NORCOLUT tablets are prescribed for a course of no more than 6 months at a dosage of 5-10 mg from days 5 to 25 of the menstrual cycle.

NORCOLUT for inducing menstruation

Gynecologists often prescribe the drug for delayed periods. Usually 2 tablets are prescribed for 7 days. After 8 days your period comes.

Menstruation after NORKOLUT

If a woman causes her period to be late, it can be painful, heavy, and with clots. With a deficiency of estrogens and gestagens, menstruation can be scanty and spotting. When treating mastodynia, premenstrual syndrome, menstruation becomes scanty and spotty - this is considered a normal reaction of the body to the drug.

NORCOLUT for abortion

A regimen for taking the drug for the purpose of abortion is prescribed only after consultation with a specialist. As soon as menstruation is delayed due to pregnancy, the doctor prescribes 2 NORCOLUT tablets for 3-5 days. During this period, menstruation should begin and the fertilized egg will be rejected.

NORCOLUT for ovarian cyst

The course of treatment and dosage is determined by the doctor. Usually the drug is prescribed in 1-2 tablets, duration - from 5 to 25 days of the menstrual cycle. The course of treatment is from 3 to 6 months.

NORKOLUT before or after meals

The drug is used regardless of food intake.

Indications for use

• premenstrual syndrome;
• anovulatory metrorrhagia;
• dysmenorrhea (accompanied by a shortening of the secretory phase);
• endometriosis;
• uterine fibroids;
• mammalgia;
• endometrial hyperplasia;
• diagnostic progesterone test;
• cessation and prevention of lactation.

Precautionary measures

With caution: bronchial asthma, chronic heart failure, epilepsy, arterial hypertension, migraine, renal failure, convulsions or other disorders of the central nervous system (including a history), diabetes mellitus, liver disease (history), hyperlipidemia, thrombophlebitis in history, history of thromboembolism.

NORKOLUT and pregnancy

The drug is not used during pregnancy. If the drug was accidentally taken in early pregnancy, the drug did not have a teratogenic effect, incl. developmental disorders of the heart and limbs. Taking the drug in the postpartum period reduces milk secretion and changes its quality indicators.

special instructions

• Before starting treatment, it is necessary to exclude the presence of malignant neoplasms and conduct a preliminary thorough gynecological, oncological examination and examination of the mammary glands.
• If the patient forgets to take the next pill, the missed pill should be taken as quickly as possible, in which case additional methods of contraception must be used.
• Norethisterone does not affect the ability to drive vehicles and operate machinery, the operation of which is associated with an increased risk of injury.

Which is better: NORKOLUT or Duphaston

NORCHOLUTH and Duphaston. vchemraznica.ru

Both drugs are not analogues of each other. Active ingredient of NORKOLUT: Norethisterone. Release form: tablets. Active component of Duphaston: Dydrogesterone. Produced in the form of film-coated tablets. Indications for use:

• endometriosis;
• infertility caused by luteal phase deficiency;
• threatened miscarriage;
• recurrent miscarriage;
• premenstrual syndrome;
• dysmenorrhea;
• irregular menstruation;
• secondary amenorrhea;
• dysfunctional uterine bleeding;
• support of the luteal phase during the use of assisted reproduction methods.

NORCOLUT can be used as a contraceptive. Duphaston can be prescribed to treat infertility and maintain pregnancy. Both drugs are available with a doctor's prescription! The choice of a particular drug is made by a specialist, taking into account the diagnosis.

The country of origin of NORKOLUTA is Hungary. Duphaston is produced in the Netherlands. Duphaston is more expensive than NORKOLUT. Price per package from 550 rub.

Is Norkolut a hormonal drug or not?

The drug belongs to the group of sex hormones and modulators of the reproductive system.

Norkolut and alcohol

Doctors do not recommend the combined use of the drug NORCOLUT and alcoholic beverages, because alcohol can reduce the effectiveness of the drug and increase the manifestations of adverse reactions.

Source: https://filzor.ru/catalog/norcolut/

special instructions

The instructions for use advise you to pay attention to the presence of special instructions. These are the following rules:

1. Before starting treatment, the presence of malignant neoplasms should be excluded and a thorough gynecological and oncological examination and examination of the mammary glands should be performed.
2. If you miss a pill, you should take it as soon as possible and additionally use non-hormonal methods of contraception.
3. Taking Norkolut does not affect the ability to operate machinery or drive a car.
4. The use of the drug during pregnancy is prohibited, but according to research, accidental use of tablets during pregnancy did not lead to teratogenic effects or disturbances in the development of the heart and limbs of the fetus.
5. Using the product after childbirth reduces milk production and reduces its quality indicators.

What are the contraindications for use?

Not every woman is allowed to use this medication. There are also contraindications to its use. Therefore, independent use of Norkolut is not recommended. It should only be used as prescribed by an experienced gynecologist. The drug is contraindicated in the following conditions:

• age less than 18 years;
• intolerance to the components included in the product;
• pregnancy planning and gestation;

The herpes virus is one of the contraindications to the use of this drug

• breast cancer;
• increased amount of bilirubin;
• oncological diseases of the genital organs;
• herpes;
• liver pathologies;
• presence of blood in the urine;
• obesity;
• inflammation or blockage of veins.

The medication should not be taken together with Phenytoin, Cimetidine and Rifampicin.

The drug is not recommended (but is sometimes prescribed under close medical supervision) for use by women with heart failure, hypertension, diabetes, various kidney diseases or epilepsy.

Drug interactions

It is also useful to study the drug interaction section in the instructions. Some combinations are prohibited:

1. Inducers of liver enzymes can speed up the metabolism of norethisterone.
2. The drug is combined with caution with hypoglycemic drugs, glucocorticosteroids, and oral anticoagulants.
3. Prohibited combinations: with Cimetidine, barbiturates, Rifampicin, Phenytoin, and other drugs that affect the process of microsomal oxidation in the liver.

Side effects

In case of an overdose of the drug, symptoms of nausea, vaginal bleeding, and vomiting are possible. Symptomatic treatment is prescribed. Side effects of Norkolut:

• headache;
• thrombosis, thromboembolism;
• breast tension;
• dyspepsia, vomiting, nausea;
• paresthesia;
• acyclic bleeding from the vagina;
• weight gain;
• increased fatigue;
• peripheral edema;
• skin rash, allergies, itching.

Possible side effects

The drug has serious side effects, especially when combined with other medications. The most common symptoms are:

• pain in the epigastric region;
• lack of appetite;
• feeling of fullness in the stomach;
• nausea;
• swelling;
• headache;
• unexplained weight loss or gain;
• hardened mammary glands.

Combining this drug with other medications may cause severe side effects. When taken simultaneously with barbiturates, metabolism accelerates and the medicinal properties of the drug weaken. Simultaneous use with liver enzyme inhibitors enhances the therapeutic effect due to a slowdown in metabolism. Cannot be combined with drugs that reduce glucose levels and insulin.

Norkolut can cause fluid retention in the body, which weakens the effect of diuretics to lower blood pressure.

Before using the drug, the patient should notify the gynecologist about the medications she is already taking, as dose adjustments may be required.

Contraindications

Norkolut for delayed menstruation or delayed lactation should be taken with caution in case of bronchial asthma, a history of thromboembolism or thrombophlebitis, chronic heart failure, hyperlipidemia, epilepsy, liver disease, arterial hypertension, brain disorders, migraine, renal failure, convulsions. The instructions highlight contraindications:

• puberty;
• herpes;
• hypersensitivity to the components of the composition;
• breast cancer or suspicion of it;
• obesity;
• diabetes;
• malignant tumors of the female genital organs;
• history of skin itching or cholestatic jaundice of pregnant women;
• suspected or established pregnancy, except in cases of miscarriage;
• bleeding of the genital tract of unknown cause;
• jaundice, acute liver disease, benign or malignant liver tumors;
• hyperbilirubinemia, cholestasis;
• renal dysfunction;
• tendency to thrombosis;
• acute thrombophlebitis, thromboembolism.

How to take Norkolut for endometrial hyperplastic processes

Endometrial hyperplasia is characterized by an abnormal process of proliferation of tissues lining the inside. Medicine distinguishes several types of hyperplastic changes, which differ in their activity and type of pathology.

If you ignore the manifestations of the disease, complications may develop that negatively affect the woman’s health.

Norkolut for endometrial hyperplasia is one of the medications that helps correct hormonal levels, disturbances of which cause the development of pathology.

Mechanism of hyperplasia

Before starting therapy, it is necessary to fully understand the causes of the disease.

The proliferation of hyperplastic pathologies occurs due to hyperestrogenism (increased estrogen production for any reason, for example, polycystic ovary syndrome).

For normal, cyclical growth and exfoliation during menstruation of the inner layer of the endometrium, it is necessary to maintain hormonal balance.

Treatment of the disease should be aimed at:

• weakening of the activity of hyperplasia development, chances of regression;
• reducing the level of heavy uterine bleeding, preventing the occurrence of anemic phenomena;
• elimination of pain;
• prevention of oncological pathologies.

Hormonal imbalance provokes the development of pathology. Therefore, therapy is not aimed at normalizing hormone levels, which Norkolut effectively copes with.

• Endometrial hyperplasia - what is it?

How does the drug work?

Norkolut helps accelerate the breakdown of estrogen, reducing their concentration in the blood. After taking the drug, the process of changing the stage of proliferation to secretion in the endometrial layer improves.

Taking Nokrkolut helps maintain the normal state of tissues when fertilized eggs are visible, for the subsequent formation of a fertilized egg, the contractility of the myometrium is significantly reduced.

Norethisterone therapy is aimed at inhibiting the production of gonadotropic hormones, which increase the activity of estrogen. This process prevents the egg from fully maturing and being released from the ovaries. Due to this, hyperestrogenism, which develops hyperplastic processes, is reduced.

Norkolut helps to equalize estrogen levels; its mild androgen action inhibits the abnormal growth of pathological endometrial cells.

Indications

Norkolut for the treatment of hyperplasia can also be used for other endometrial diseases.

The drug is prescribed for the following symptoms:

• severe premenstrual syndrome;
• reduction in the secretory phase of the menstrual cycle;
• pain in the mammary glands;
• uterine bleeding that appeared during menopause;
• adenomyoma of the uterus;
• If it is necessary to stop or prevent the onset of lactation.

For various forms of diseases, this medication is often combined with other drugs. In most cases, it must be used together with general strengthening agents (immunostimulants, vitamins, mineral complexes). For hyperplasia in an overweight woman, the doctor prescribes physical activity and diet.

Contraindications

In addition to its positive properties, Norkolut has contraindications for use. These include:

• formation of possibly malignant tumors;
• puberty;
• individual intolerance to the components of the drug;
• pregnancy period;
• severe liver diseases such as hepatitis;
• hemorrhages of unknown origin;
• increased blood clotting;
• renal failure;
• high blood pressure, diabetes.

Before starting to take the drug, the patient must undergo a series of studies, a thorough examination by a gynecologist and mammologist, and take a blood test for hormones.

If, during examination, the patient is diagnosed with depression, the drug is prescribed in small courses with a minimum dose, and is discontinued if the depressive state begins to progress.

Possible side effects

The drug has serious side effects, especially when combined with other medications. The most common symptoms are:

• pain in the epigastric region;
• lack of appetite;
• feeling of fullness in the stomach;
• nausea;
• swelling;
• headache;
• unexplained weight loss or gain;
• hardened mammary glands.

Combining this drug with other medications may cause severe side effects. When taken simultaneously with barbiturates, metabolism accelerates and the medicinal properties of the drug weaken. Simultaneous use with liver enzyme inhibitors enhances the therapeutic effect due to a slowdown in metabolism. Cannot be combined with drugs that reduce glucose levels and insulin.

Norkolut can cause fluid retention in the body, which weakens the effect of diuretics to lower blood pressure.

Before using the drug, the patient should notify the gynecologist about the medications she is already taking, as dose adjustments may be required.

Regimen and dosage

Instructions for use of the drug will help you find out more information about its features. However, this information most often helps the doctor rather than the patient. Norkolut is produced in the form of tablets. They contain norethisterone and other excipients.

The regimen for using the medication directly depends on the individual characteristics of the disease. If hyperplasia is diagnosed, you can take the medicine in several short courses (1-2 weeks), 1-2 tablets. If uterine bleeding weakens or disappears, the patient should stop taking Norkolut. You can continue taking it for preventive purposes on certain days of menstruation.

The gynecologist needs to carefully analyze the individual characteristics of the patient in order to prescribe the correct dosage and course of therapy.

Norkolut for endometriosis

The basis of treatment for endometriosis is hormonal drugs.

Depending on the type and degree of development of the pathology, the doctor may prescribe estrogen and progesterone antihormones or estradiol and gestagen-containing medications. Norkolut belongs to the latter type of drugs. It is a gestagen with a weak therapeutic effect, so it is ideal for treating the initial stages of pathology.

Prices for Norkolut

The price of Norkolut may vary, depending on the region and pharmacy. The average cost of the drug is 125 rubles. The budget price makes the drug quite affordable for the population.

Analogs

Norkolut is an effective remedy for the treatment of endometriosis. It has many analogues that are similar in characteristics (composition, indications, treatment regimen).

It is categorically not recommended to independently look for a replacement for the medications prescribed by the attending physician - only a specialist can do this, taking into account the individual characteristics of the pathology.

Popular analogues of Norkolut:

• Duphaston;
• Logest;
• Jazz;
• Yarina;
• Janine;
• Lindinet;
• Hydrocortisone;
• Triderm;
• Diana is 35.

Terms of sale and storage

Norkolut is a prescription drug that is stored at a temperature of 15-30 degrees for five years out of the reach of children.

To replace the product, you can select drugs with a similar composition or effect. These include:

• Primolut-nor is a hormonal tablet preparation containing norethisterone.
• Orgametril - progestogen tablets based on linestrenol.
• Pregnin is an ovulation stimulator in the form of a solution containing ethisterone and progestogen.

Norkolut pregnancy

I don’t know why I’m writing at all. Everyone is so joyful and happy. I'll ruin everything here with my vile mood