Generics
The popular remedy soon had analogues. Based on the Fluconazole component, the following were developed and went on sale:
- Diflazon (KRKA),
- Mikosist (Gedeon Richter),
- Mycoflucan (Dr. Reddy's),
- Mycomax (Zentiva)
- Flucostat (Pharmstandard),
- Fluconazole (Sandoz).
Dozens of pharmaceutical companies, both domestic and foreign, produce the drug under the trade name “Fluconazole”. How quickly fluconazole acts against thrush depends on the degree of purification of the raw materials.
When do the symptoms of thrush disappear after taking fluconazole - All about thrush
How to take Fluconazole for thrush? This question interests many women, because they often neglect to visit a doctor and try to treat candidiasis on their own using a popular, inexpensive Russian-made drug.
Indeed, today Fluconazole is considered one of the most accessible and at the same time effective antimycotics for systemic action. However, before using this remedy, it is very important to learn as much as possible about its action and rules of use for candidiasis.
Often, experts advise only local treatment of vaginal candidiasis, prescribing women antifungal suppositories, creams and ointments. However, external therapy does not always help get rid of the disease.
If thrush often recurs, does not go away for a long time or is severe, complex treatment is necessary, which involves the mandatory use of antifungal tablets, in particular Fluconazole.
What is this medicine? Fluconazole capsules are an antimycotic drug containing an active substance with the same name. Fluconazole:
- effectively fights pathogens of vaginal candidiasis at the cellular level;
- destroys their structure;
- stops growth and further reproduction.
The drug is indicated for use in chronic thrush and acute genital candidiasis, as well as for the prevention of relapses of the disease in women and men suffering from fungal disease more than 4 times a year.
Due to its low cost, Fluconazole is the most affordable drug in its class. The cheapest capsules can be purchased for about 10–12 rubles. Foreign analogues (Diflucan, Flucostat, Mikosist and others) are many times more expensive, but it is noted that domestic Fluconazole is often inferior to them in effectiveness.
When taking Diflucan and Flucostat, according to the instructions, you need to drink only 1 capsule to achieve the desired result, while the Russian-made product often needs to be taken for several days.
Nevertheless, many women still drink Fluconazole and are satisfied with the effect of the drug, claiming that it helps get rid of thrush quickly and inexpensively.
Many women are interested in how to take Fluconazole. Although the drug can be easily purchased at any pharmacy without a doctor's prescription, you should not rush to purchase and uncontrolled use of the drug: this drug can be used only after confirmation of the diagnosis and exclusively as prescribed by a doctor.
The specialist will take into account all the characteristics of the patient’s body, determine the severity of the disease and determine what dosage of Fluconazole will help eliminate the infection in a particular case. It is important to remember that capsules are incompatible with some medications and can be harmful if used incorrectly.
Fluconazole tablets may contain 50, 100 or 150 mg of active ingredient. The instructions for using Fluconazole for thrush in women states that to get rid of symptoms, it is enough to drink 1 capsule of the drug with a dosage of 150 mg.
However, you should not completely rely on the annotation: depending on the form and severity of candidiasis, you may need to take the drug multiple times. At the discretion of the doctor, a different treatment regimen may be chosen. For example, gynecologists often advise treating vaginal candidiasis as follows:
- On the first day, take 1 tablet of Fluconazole (150 mg dosage). After 3 days, repeat taking the capsule. This dosage regimen is generally recommended for mild to moderate fungal infections with an acute course. If the therapy has no effect, the course of treatment can be repeated, and at the discretion of the specialist, the dose of the drug is increased.
- Taking Fluconazole for chronic thrush involves taking 1 tablet (150 mg) once a month for a long time (the duration of preventive therapy is determined individually). It is first necessary to relieve the symptoms of exacerbation of the infection using the method of using the product described above.
Of course, these schemes are presented here for informational purposes only, and should not be used as a guide when treating candidiasis. Before taking Fluconazole for thrush, you must visit a doctor.
Often women are interested in how quickly Fluconazole helps. It is impossible to unequivocally answer the question of how long it takes for thrush to go away after taking Fluconazole. The effectiveness of therapy largely depends on individual indicators - the severity of the disease, the susceptibility of fungi to the drug, the level of immunity and other factors.
However, this does not always mean complete recovery. To make sure that the fungal flora is destroyed and the disease has really gone away, it is necessary to do a smear test for the presence of infectious agents, otherwise the thrush may return in a short time and develop with renewed vigor.
Treatment of thrush with Fluconazole should be under the strict supervision of a doctor, since this drug is considered a potent antifungal drug and has certain contraindications. These include:
- individual intolerance to the active substance;
- simultaneous use of certain medications (terfenadine, astemizole, cisapride, quinidine);
- lactation;
- 1st trimester of pregnancy.
It is recommended to use the drug with extreme caution for those who suffer from liver problems, since in some cases Fluconazole can provoke toxic damage to this organ.
The use of the drug should not be combined with the use of hepatotoxic drugs. In addition, the drug can be harmful in case of renal failure, so people suffering from this pathology must consult a doctor before starting antifungal therapy.
Fluconazole has a negative effect on the fetus, and for this reason it is not prescribed in the 1st trimester of pregnancy. It is not recommended to use the product at later stages of gestation in order to avoid negative consequences for the child’s health.
However, the doctor may prescribe Fluconazole to the expectant mother if the fungal infection is severe and cannot be treated with topical medications. As a rule, this occurs only in cases where the expected benefit from the use of Fluconazole far outweighs the potential risk of complications.
Rarely, but still there are situations when an antimycotic causes side effects. The most common among them are:
- digestive disorders;
- headache;
- skin allergic reactions.
If one or more of the side effects listed in the annotation occur when using the drug, you must stop taking the medication and inform your doctor.
Fluconazole for thrush in women is an inexpensive, accessible and effective remedy, so it is often preferred by the fairer sex. It is easy to purchase and use, but candidiasis can be treated with this drug only in consultation with a specialist.
Fluconazole is a common antifungal agent and is of synthetic origin. Belongs to the pharmaceutical group of triazoles, used for the treatment and prevention of thrush, mycoses and some other pathologies.
How long does it take for Fluconazole to start working? The drug begins to work 1.5 hours after use, and the therapeutic effect in many patients is observed after different times, which is due to the individual characteristics of the body and the specific disease.
Composition and description
The drug is produced in capsule and tablet form, in the form of a gel, syrup, solution for intravenous use, and suppositories. The main active ingredient is the same name of the drug.
You can buy different dosages of the medicine - 0.1 g, 0.05 g and 0.15 g. The capsules are characterized by a blue tint; inside there is a powder with a granular structure - the color is white or slightly yellowish - a variant of the norm. The medicine is sold in cardboard packs containing a blister.
For information, Fluconazole is used as an antifungal drug that has high biological activity against various microorganisms of the Candida spp group, cryptococci, Trichophytum spp and Microsporum spp.
After taking Fluconazole, there is a detrimental effect on fungal enzymes. The active substance blocks the transformation of ergosterol in the cells of pathogenic microorganisms. Under the influence of the drug, an increase in the permeability of the cell membrane and inhibition of the process of pathogen activity are observed.
After taking capsules/tablets, the substance fluconazole is absorbed in the human gastrointestinal tract. How long does it take for it to start working? It is difficult to answer this question accurately, since the effect of any medication depends on the individual physiological characteristics of the body. The pills help some people quickly, while others have to wait a certain time.
According to the instructions, the maximum concentration of fluconazole is detected eight hours after use, but in reality the component begins to work earlier. One tablet is effective for three days, so the symptoms should be completely eliminated during this time.
According to doctors, the drug is quite effective against various strains of pathogenic and opportunistic microbes, therefore it is often used in the treatment of various pathological processes.
Pharmacological forms
- IV solution with an active ingredient concentration of 200 mg / 100 ml volume;
- powder for preparing suspension (Diflucan);
- Fluconazole tablets containing 50, 100 or 150 mg of the active substance (for example, Mikoflucan, it is used for long courses of treatment of chronic infection);
- gel with a concentration of 5 mg / 1 g volume (Flucorem);
- syrup used at a dosage of 3 mg/kg body weight per day (Mikomax; aimed at children and patients with swallowing problems);
- capsules with a concentration of the active component of 50 mg (Flunol), 100, 150 (Flucomicide Sediko) and 200 mg (Forkan, Ciskan), number per package: 1, 5, or 7 (recommended if you need quick and more complete, in terms of bioavailability , result).
Due to the variety of forms, the possibility of multifactorial influence on the infectious agent is possible, which leads to a good therapeutic effect.
Side effects are described in detail in the instructions. Judging by the reviews, gastrointestinal problems occur more often than others: nausea, bloating, gurgling, mild abdominal pain, diarrhea. In isolated cases - migraine, rash, hair loss.
Copy problem
Domestic capsules are much cheaper than the original. Fluconazole has become available to all segments of the population. The problem was that it was possible to register a drug created not only on the model of the original Diflucan, but also on its generics.
The discrepancy in composition turns out to be significant if the new drug is manufactured from the fifth or tenth copy of the original. In addition, there is a difference in the base, auxiliary components, and capsule composition.
Generic drugs can be either bioequivalent to the original drug or different from it. Fluconazole in different pharmaceutical products differs in quality. Also, despite the same formula of the active substance, the drugs may differ in dosage.
Whether Fluconazole helps with thrush depends on the quality of the purchased generic and the individual characteristics of the body. For some, a cheap analogue will be enough. Some girls prefer not to overpay for Diflucan, buy medications for 35-40 rubles and cope with candidiasis quite effectively.
Treatment of chronic candidiasis in pregnant women
If thrush does not go away during pregnancy, the doctor is very limited in the choice of drugs suitable for the patient. Medicines approved for any period of time (Pimafucin and Clotrimazole in the form of suppositories) do not give results in the chronic form, and the most effective drugs - with fluconazole and itraconazole - are contraindicated for pregnant women.
If suppositories allowed during pregnancy provide a temporary improvement, and the patient’s general condition remains stable and the infection does not spread, then it is necessary to use only them, treat the skin daily with local antiseptics, and observe the rules of personal hygiene of the genitals more strictly than usual.
Full treatment that eliminates fungi is prescribed after childbirth (in this case, breastfeeding will have to be abandoned).
If a pregnant woman’s thrush does not go away, the doctor decides what to do and in most such cases prescribes examinations that reveal diseases of the immune and endocrine systems (they may not have manifested themselves before pregnancy). If the patient's condition worsens, the following measures are necessary:
- hospitalization;
- use of antifungal tablets;
- in severe cases, use intravenous solutions.
After therapy, examination of the fetus is necessary. If the health of the unborn baby is irreparably harmed, the woman may be offered termination of pregnancy.
All these consequences can be avoided if you undergo a full examination and, if necessary, treatment when planning a pregnancy. It is best to make an appointment with a doctor not only for the woman, but also for her husband, in order to minimize the risks for the expectant mother and baby. However, we should not forget that significant hormonal changes occur during pregnancy; it is impossible to fully know its consequences in advance, and you need to be prepared for unpredictable changes in your condition and well-being.
Fluconazole for men against thrush
Until recently, male thrush seemed like a common myth. Today we know that candidiasis in men is a very real disease that affects the mucous membranes of the genital organs. There are different approaches to treating candidiasis.
Thrush in men is not as common as female candidiasis due to the difference in the anatomy of the genital organs. The fact is that it is extremely difficult for the thrush pathogen to stay on the external genitalia of a man. Infection can only occur in conditions of weakened immunity.
Instructions
Instructions for use of Fluconazole indicate that the drug is used not only to treat vaginal infections, but for other diseases. The drug can be prescribed in the following cases:
- meningococcal infection - 400 mg per day, or 8 tablets of 50 mg;
- invasive candidiasis (damage to internal organs due to infection) - 400 mg on the first day, 200 mg the rest of the time of treatment;
- skin candidiasis - 150 mg;
- mycosis of the groin, feet - 150 mg every 7 days,
- candidiasis of the oral and pharyngeal mucosa - 150 mg per day.
Important! The drug should be taken with caution in case of liver damage, kidney disease, or when taken simultaneously with anticoagulants. Do not give Fluconazole to children under 3 years of age. Individual intolerance may occur in adults.
Treatment during pregnancy is possible if there is a risk to the fetus, but the use of the drug is not advisable. It is not known how the drug affects the development of the child. During pregnancy, only the doctor determines the possible risks and decides whether to prescribe Fluconazole or make do with suppositories and ointments. The drug should not be taken during breastfeeding as it passes into human milk.
Contraindications and side effects of Fluconazole
The drug is prescribed with extreme caution if there is a history of liver disease or superficial fungal infections. Based on the results of laboratory tests, the doctor may adjust the dosage downward.
Fluconazole is not prescribed in the following situations:
Anti-worm suppositories for children and adults
- Hypersensitivity to the active component or azole substances, which are characterized by similarity to the structure of fluconazole;
- It is prohibited to combine Fluconazole and Terfenadine if the treatment involves a dosage of the first drug of 0.4 g per day;
- Children up to 4 years old.
It is worth knowing: the parallel use of Astemizole and other drugs that help increase the QT interval is strictly prohibited.
Adverse reactions of the body include pain in the epigastric region, digestive disorders, increased formation of gases in the intestines, and allergic reactions. The development of angioedema due to intolerance to the composition of the medication cannot be ruled out.
During pregnancy, capsules and tablets are prescribed extremely rarely, only for strict medical reasons, when women have already been diagnosed with a severe fungal process in the body. The drug passes into breast milk; lactation should be discontinued during the treatment period.
If alarming symptoms develop, the question of further treatment is decided individually by a medical specialist. The specific symptom, its intensity and severity, the patient’s condition, and other points are taken into account. In some cases, treatment continues despite side effects, sometimes requiring a change in drug.
The drug didn't help
It happens that fluconazole does not help with thrush, what should you do in this case? In approximately 10% of cases, thrush is difficult to treat, and in 2% of women the drug does not help at all. The ineffectiveness of the drug is explained by the fact that some fungi of the genus Candida are resistant to the medication. In this case, culture will be required in the laboratory to identify the pathogen.
If fungi are resistant to the Fluconazole component, other drugs are used: Miconazole, Nystatin, Polygynax, Clotrimazole, Mikosist, capsules with fenticonazole.
Most women looking for an effective remedy to combat the annoying candida fungus have come to the conclusion that flucostat is the best medicine for thrush. Is this really so and does flucostat help against thrush for everyone who purchases this treasured capsule? Let’s try to figure it out.
For candidiasis, flucostat is prescribed because its active ingredient is the well-known fluconazole. The triazole antifungal drug is very effective against most fungi and has a fairly wide range of applications.
In addition, many other drugs that are among the ten best antifungal drugs are made based on fluconazole. These are Russian tablets Fluconazole, French Diflucan, Slovenian Diflazon, Indian Fucis and Forkan.
Despite the fact that their names are so different, as well as the price per package, they all have almost the same effect and are bioequivalent. Moreover, the capsule for thrush, flucostat, is nothing more than a generic version of the French advertised drug Diflucan, because the Russian medicine appeared after the patent for the original drug had expired.
The medicine has a specific effect, which is aimed at reducing the activity of fungi. The drug is able to block the process of converting lanosterol into ergosterol, which disrupts the structure of fungal cells and contributes to its destruction.
The active substance is Fluconazole.
Application
Treatment is carried out if the discharge increases and becomes cheesy in nature, and itching and burning appear in the genital area. If these symptoms are not eliminated in time, pain will occur when urinating. Fluconazole is recognized as the best drug in the fight against genital candidiasis.
Thrush affects about 70% of women and a small percentage of men. Fluconazole is used according to the instructions. The drug is prescribed orally, the dosage is determined by the doctor. Therefore, the question arises: How should I take Fluconazole for thrush? Capsules are taken according to the following treatment regimen:
- a single dose for the prevention of candidiasis after antibiotic therapy at a dosage of 150 mg;
- two-day intake of 150 mg;
- every day, one capsule 150 mg for 3 days;
- 7 days 150 mg;
- 1 capsule of 150 mg every 3 days;
- 150 mg once and another 150 mg on the first day of the next menstruation.
If taking tablets or capsules is contraindicated, Fluconazole is administered intravenously. As is the case with capsules and tablets, the treatment regimen for thrush with Fluconazole is selected depending on the characteristics of the patient’s body and the stage of development of the disease.
Thrush is not a sexually transmitted disease, but if sexual intercourse occurs with a person who is sick with candidiasis, then the disease passes to a healthy person. You can often hear the question: when does thrush go away after taking Fluconazole?
The medicine helps with thrush quite quickly. But it all depends on the severity of the pathology and the patient’s immunity. Often, women themselves stop the course of treatment after the result has been achieved, but in this case the disease is not fully cured and therefore returns again.
Side effects
The treatment regimen is determined by the doctor depending on the severity of the disease, as well as the presence of other infections, because often candidiasis usually develops simultaneously with STIs. In most patients, treatment of thrush with Fluconazole occurs without side effects. But the following symptoms may develop:
- headaches and dizziness;
- dysfunction of the liver and kidneys;
- nausea, diarrhea;
- allergies: skin rash, facial swelling, urticaria;
- change in taste;
- hallucinations, but this happens with an overdose.
Side effects can be observed only in 15% of cases, in those suffering from allergic reactions and disorders of the gastrointestinal tract.
Contraindications
During treatment for thrush, you should be sure that there is no pregnancy. The drug should not be used by pregnant women. Scientists were able to prove that when taking Fluconazole tablets during pregnancy (in the first trimester), the risk of developing heart defects in the child increases.
The presented drug is not the best way to combat thrush in children under 4 years of age. It is also not recommended to use it simultaneously with astemizole and terfenadine. Fluconazole should be used with caution in case of renal and liver failure and heart disease.
Before taking Fluconazole for thrush, you should be aware of all contraindications and side effects in order to avoid unwanted reactions. Contraindications include:
- children under 4 years of age;
- lactation period;
- pregnancy;
- drinking alcohol;
- hypersensitivity to the drug.
The drug should be used with caution in people:
- with renal or liver failure;
- while taking Terfenadine.
Before starting treatment, you should definitely consult a doctor. Any medicine can be beneficial, but in some cases it can also harm the body.
Medicinal properties of the drug
In most cases, the development of thrush is a consequence of damage to the mucous membranes by the candida fungus. Therefore, you can get rid of the infection only with the help of antifungal agents.
Among the most effective systemic mycotics recognized throughout the world is the drug Fluconazole, created on the basis of the active substance of the same name.
The activity of fluconazole is expressed in a powerful effect on the production of fungal enzymes necessary to ensure its vital processes. Due to the inhibition of ergosterol, the supply of nutrients to the fungal spores is stopped. The processes of growth and reproduction stop and after some time the fungus dies.
Therefore, after you start taking Fluconazole, thrush quickly goes away, and the unpleasant symptoms of the infection disappear forever.
Release forms
For ease of use, Fluconazole is available in several pharmacological varieties:
- tablets and capsules - for oral administration;
- syrup - for the treatment of children with oral mucosa affected by thrush;
- injection solution - used for severe forms of infection;
- powder for suspensions.
Dosage of tablets and capsules is 50 mg, 100 mg and 150 mg. The composition of the drug is identical in all types of dosage forms.
Maybe it's not candidiasis
In the treatment of infections caused by the candida fungus in men, women and children, the drug fluconazole for thrush helps quickly. The drug is the best in all respects, from the rapid action of fluconazole against candidiasis, to the incredibly low price of the drug in a number of drugs belonging to the group of antifungal agents to combat not only candida, but also a number of other fungi and viruses that cause lichen, dandruff and others skin diseases.
What is this unique medicine, which is so rarely prescribed by a doctor and which pharmacies are so reluctant to offer, and how to cure thrush with fluconazole, will be discussed below.
This is an antifungal agent that has a fairly wide spectrum of highly specific action, helping to inhibit the activity of fungal enzymes. It increases the permeability of cell membranes, blocks the formation of ergosterol, stops cell growth and replication.
The domestic manufacturer produces fluconazole against thrush for men and women in the form of:
- capsules
- tablets
- syrup
- suspensions
- solution for injection and infusion
Sometimes, instead of our domestic drug, which costs about 20–30 rubles, they offer the same imported product. A widely used drug for thrush is fluconazole Teva (FLUCONAZOLE-TEVA), produced in Hungary.
The drug fluconazole STADA, produced in Russia, is also becoming widespread. Both of these agents (Teva and STADA), as well as their foreign analogues with the same active ingredient (Diflucan, Mycomax, Diflosan, Flucostat and a number of others) have the same effect on microorganisms.
Before you start using fluconazole for thrush in a man or woman, you must visit a doctor. Depending on the severity of the disease, treatment regimen and clinical picture of the disease, the doctor determines the individual dosage of the drug.
And even after undergoing a full examination and receiving doctor’s advice on how to take or drink the drug when treating candidiasis, do not rush to use the medicine. First, you need to carefully study the instructions for using fluconazole for thrush.
- Intravenously when treated with injection solutions
- Intravenous drip when using solution for infusion
- Swallowing, without chewing, with water, when prescribing tablets
- Diluting in water, when prescribing powders for suspensions
With each of these methods of using fluconazole for candidiasis, there may be side effects from various organs:
- Digestive system: stomach pain, flatulence, vomiting, diarrhea, jaundice, dyspepsia, liver problems
- Nervous system: headache, seizure
- CVS: ventricular fibrillation, increased QT interval on ECG
- Skin manifestations: rash, itching, swelling of various parts of the body, alopecia
- Metabolism: Triglycerides and bad cholesterol levels increase
- Allergic reactions
If Fluconazole does not help with thrush, the reason may be an incorrect diagnosis. In the modern world, many people do not find time for a doctor, and the state of public medicine leaves much to be desired.
Usually women grab the first drug they come across at the pharmacy, without understanding the symptoms. Vaginitis (inflammation of the vaginal mucosa), genital herpes or a sexually transmitted infection can be mistaken for thrush. STDs are not that uncommon; you can get infected from the ground floor and even from using other people’s things.
STDs include:
- gonorrhea,
- chlamydia,
- trichomoniasis,
- syphilis.
Mycoplasmosis and ureaplasmosis are not considered sexually transmitted diseases. Mycoplasma, ureaplasma, and gardnerella live in the body of every woman, but if they go wrong they can cause bacterial vaginosis. In this case, restoration of the microflora will be required.
Candida fungi are present in the body of every woman. Gardnerella and other microorganisms are also present in the body. Normally they do not cause concern. When immune failure occurs, the number of bacteria increases. Discharge and inflammation appear.
An increase in the number of Candida is often associated with intestinal dysbiosis. Intestinal problems arise due to improper antibiotic therapy. Proper treatment usually does not cause intestinal problems.
Antibacterial therapy was previously carried out simultaneously with antifungal therapy to avoid the development of candidiasis. As it turned out, such measures were ineffective. Carrying out antifungal therapy along with taking antibiotics had no effect on the development of candidiasis.
When treating candidiasis, it is important to establish the root cause, that is, to find out what in the body led to immunodeficiency.
Indications for use
The medication may exhibit side effects during therapy if taken for a long time. As a rule, treatment of acute thrush is not accompanied by adverse events.
Common side effects include:
- headache;
- dizziness;
- perversion of taste;
- epigastric pain;
- nausea and diarrhea;
- allergic rash;
- decreased leukocyte levels;
- lipid metabolism disorders;
In some cases, hepatitis and jaundice may occur.
Contraindications include:
- pregnancy;
- breast-feeding;
- age up to one year;
- individual intolerance.
For kidney diseases, the drug is prescribed in a lower dosage.
Taking Fluconazole is prohibited if:
- increased sensitivity of the body to the active component of the drug;
- breastfeeding a child;
- age category up to five years;
- 1st trimester of pregnancy;
- combined treatment with Cisapride.
Increased caution when taking Fluconazole occurs due to:
- 2nd and 3rd trimesters of pregnancy;
- impaired digestibility of lactose;
- malfunctions of the liver and kidneys;
- simultaneous use with Terfenadine;
- abnormal heart rhythm.
The instructions indicate that you should not continue treatment of thrush with fluconazole if you are hypersensitive to the active substance. It is not recommended to take Fluconazole for children under 4 years of age, as well as for patients using the drugs Terfenadine, Astemizole.
During pregnancy, it is not recommended to treat candidiasis with Fluconazole, except in severe cases that threaten the woman's life. If the disease arose during this period, suppositories or ointment for topical use would be preferable.
Genital herpes
If we talk about why fluconazole does not help with thrush, then the reason may be genital herpes. This is a common viral infection that is sexually transmitted. The disease is caused by the herpes simplex virus (HSV).
Herpes may be accompanied by scanty discharge, itching, and pain during sexual intercourse. Herpes in many cases causes chronic candidiasis, which is difficult to treat. When getting rid of thrush, you will first have to treat the herpes infection.
It is especially necessary to undergo treatment before planning a pregnancy, since many drugs will be banned after conception. In addition, HSV can lead to malignant tumors of the cervix.
Another reason why tablets for thrush do not help lies in the partner. All sexually transmitted infections must be treated together with the man, and candidiasis is precisely this type of disease.
How to treat chronic thrush
If the thrush does not go away after treatment, the doctor will tell you what to do first, prescribing a second course of therapy. What exactly will be prescribed depends on how the patient was treated before. During the repeat course, it is important to strictly follow the rules for taking medications and hygiene standards. You should not interrupt treatment earlier than indicated in the instructions, especially you cannot refuse to use the drugs.
When repeating the course, the doctor will most likely prescribe not only local remedies, but also tablets, for example, Fluconazole or its analogues. Taking tablet medications takes from 3 to 6 days. Unlike acute, chronic thrush does not go away after Fluconazole with a single use. In addition, restorative and immunostimulating agents and procedures may be prescribed.
To decide what to do if thrush does not go away during treatment with hormonal agents, immunosuppressants or antibiotics, the attending physician will review the treatment regimen or prescribe additional drugs against candidiasis.
If thrush in men does not go away, then this is also most often due to improper treatment - the effectiveness of local remedies in the stronger sex is lower, so it is advisable to eliminate thrush with antifungal tablets before candidal urethritis develops. If the disease has already become chronic, then a single use of Fluconazole in tablets will not be enough.
If the initial and repeated courses of therapy were carried out correctly, but turned out to be ineffective, the patient does not take any drugs that impair the immune system, but the thrush does not go away after treatment, what should the patient do? In this case, you need to undergo examinations for a number of immune and endocrine diseases (the doctor must write a referral). Most likely, they are the cause of chronic candidiasis.
Additional measures
When treating women, they are interested not only in how long it takes for Fluconazole to act for thrush, but also how quickly the itching and inflammation of the vagina (colpitis) will disappear. The drug acts gradually, usually in the first day, but the itching needs to be relieved instantly.
To eliminate discomfort, Epigen Intim spray is additionally prescribed. The spray is used up to 4 times a day, spraying 1-2 times inside the vagina. The spray will relieve itching and also help restore normal vaginal microflora, disturbed by taking antifungal medications. To completely restore the microflora, use the spray for 10 days.
During pregnancy, systemic drugs are not used due to their toxicity. The use of local medications (Pimafucin) is allowed. Additionally, the vagina can be treated with furatsilin solution.
Non-pregnant women can use drugs with nystatin and clotrimazole for local treatment. For local treatment, suppositories and sometimes ointments and gels are usually used.
Speaking about how long it takes for thrush to go away after taking fluconazole, you should remember that if in the first days there is no improvement and reduction in symptoms, the drug may not be suitable. In this case, Fluconazole is replaced by other antifungal drugs.
During pregnancy
Adequate and controlled studies on the effect of Fluconazole on a pregnant woman and unborn child have not been conducted. Medicine for thrush is strictly prohibited in the first trimester of pregnancy due to the possible development of heart pathologies in the fetus. In the future, the doctor analyzes in each specific case the negative consequences of taking Fluconazole in the treatment of thrush.
It is better to use contraception before planning pregnancy when treating candidiasis.