Every woman experiences pain, cramps and other unfavorable symptoms during her menstrual period. The pharmaceutical market offers a large selection of drugs that alleviate the condition during the cycle. Taking the appropriate pain reliever is the best solution to the problem. One of the medications recommended by gynecologists is Nise for monthly bleeding.
Characteristics of the product
The wide spectrum of action of the tablets has led to their use for various diseases or health problems. What the drug helps with, the rules of administration and contraindications are indicated in the instructions.
Composition and indications for use
Nise is a non-steroidal anti-inflammatory drug with a broad range of analgesic and antipyretic effects. The main substance is nimesulide. Its amount is 50 or 100 mg. Auxiliary elements: starch, silicon dioxide, flavoring additives. The medicine is sold in the form of tablets, gel and suspension for children.
Indications for use:
- pathologies of the musculoskeletal system;
- pain in muscles, joints and lower back;
- increased temperature;
- pain syndrome and inflammatory process.
Every woman during her period is accompanied by nagging pain in the lower abdomen, nausea and other symptoms. The drug is quickly absorbed into tissues and rarely causes negative effects. Prostaglandins are present in large quantities in the body and stimulate uterine contractions. This leads to muscle spasms. The effect of Nise for menstrual pain is explained by a decrease in the amount of prostaglandins, histamine, blocking of free radicals and interaction with glucocorticoids. The movement of the pain impulse to the brain stops, and the unpleasant sensation recedes.
Nise tablets during menstruation improve a woman’s overall well-being. The drug is considered less harmful to the liver than its analogues. Medical professionals advise not to endure pain, since in such circumstances blood pressure increases, the pulse quickens, and disturbances in the hormonal system occur, which can lead to more troubles for the body.
Dosage and rules of administration
With a wide spectrum of action, you need to know how to take the pills correctly depending on the problem that arises. Taking the drug is different for different types of pain.
Children from 3 to 12 years old take the medicine in the form of syrup or tablets. The ratio is 3−5 mg per 1 kg of child weight. The highest dosage for an adult is 2 tablets up to two times a day. At any time, regardless of diet. The maximum course of treatment is 10 days.
Dosage for deterioration of health:
- toothache - take 50 mg 1-2 times a day;
- migraine - 100 mg 2-3 times a day;
- high temperature - 1 tablet up to 4 times a day (maximum 400 mg per day);
- discomfort during menstruation - 1 tablet twice a day.
Drinking Nise for menstrual pain is allowed if the woman follows the instructions and has no restrictions on the use of the medicine. You can double the dosage if there is no analgesic effect. If your health does not improve, you need to consult a specialist. In adolescence, the cycle is irregular, so the maximum dosage, calculated from the ratio of the girl’s weight, should not exceed two tablets per day.
Often during pregnancy, women experience pain: in muscles and joints as a result of increased pressure on the musculoskeletal system, dental pain due to a lack of calcium. Gynecologists advise choosing an analgesic medicine suitable for pregnant women. If the patient took Nise and became pregnant, it is necessary to stop therapy as soon as possible and consult a doctor. Such a pregnancy should be under the supervision of specialists.
The attending physician should be aware of the patient's chronic illnesses before recommending the pills. Among the reviews about the drug there are many positive ones. Of these, rapid pain relief is noted and the effect lasts up to 8 hours.
Contraindications and side effects
Due to the high content of the active ingredient, Nise tablets are not suitable for all patients. People with diseases of the digestive tract and related organs should avoid this medicine. Even a small amount of nimesulide taken can cause bleeding or serious consequences. In accordance with the annotation for the medicine, there are a number of restrictions on use.
Contraindications:
- sensitivity to nimesulide and other components of the composition;
- worsened asthma, polyposis;
- erosion and ulcerative lesions of the stomach or intestines;
- addiction;
- intestinal infection;
- allergy to Aspirin;
- abnormal blood counts;
- concurrent use of hepatotoxic drugs;
- hyperkalemia;
- pregnancy and feeding;
- children under two years of age;
- renal failure.
The analgesic should be used with caution in patients with heart and vascular diseases, diabetes mellitus, stomach ulcers, infection with the Helicobacter bacteria, in old age and in cases of nicotine abuse.
The pills are contraindicated for pregnant and lactating women because they can cause great harm to the health of the expectant mother and baby. Nimesulide enters the baby's body through breast milk and poses a great danger.
Adverse reactions:
- hives and other skin rashes;
- anaphylactic shock;
- dizziness, headache;
- nightmares, sleep disturbance;
- diarrhea, constipation;
- exacerbation of gastritis, ulcers;
- nausea, vomiting;
- impaired blood hemodialysis;
- hepatitis, jaundice;
- increased asthma, bronchospasm;
- heart rhythm failure;
- increased blood pressure;
- convulsions.
Negative manifestations are possible in case of excessive use or uncontrolled use of the medicine. With long-term use, it is necessary to monitor the functioning of the kidneys and liver.
Before prescribing, you need to make sure that pain during menstruation is caused precisely by the onset of the cycle, and not by an exacerbation of the disease. Responsible use of Nise will protect you from harm to health.
Special Purpose
The drug should not be used in combination with various medications. You need to be careful about work that requires high concentration. To prevent pain, analogues of Nise are used, which are not inferior to it in effectiveness.
Drug interactions and other conditions
The tablets are not recommended for use in combination with Digoxin, Phenytoin or lithium preparations. Under the general influence, the therapeutic effect decreases. When using hypoglycemic drugs, it is necessary to constantly monitor the level of sugar in the blood plasma.
If antihypertensive treatment is prescribed, the patient's blood pressure decreases. This interaction is not desirable. The use of anticoagulants is not recommended due to the high risk of internal bleeding. The same goes for non-steroidal drugs.
During treatment with Nise, visual impairment and dizziness occur, so you should not drive or operate equipment that requires a lot of concentration.
Substitutes and similar drugs
During the days of the menstrual cycle, the most painful sensation is abdominal pain. Each girl has her own ways of eliminating it. Doctors often recommend Nise for pain during menstruation. The pharmaceutical market offers a wide range of drugs with similar composition or action.
Analogues:
- Nimesulide.
- Actasulide.
- Aponil.
- Tempalgin.
- Analgin.
- Mesulide.
- Nimulid.
- Sedalgin.
- Ketonal, Ketorol, Ketanov.
- No-shpa.
- Spasmalgon.
- Pentalgin.
- Drotaverine.
- Citramon.
- Diclofenac.
- Nimesil.
- Aspirin.
If a girl’s menstruation began very early - at 10-11 years old, she will have to look for an alternative, since drugs with nimesulide are contraindicated for children under 12 years of age.
Nimesulide, Actasulide and Aponil are the cheapest analogues of Nise. Foreign production has proven the medicine on the Russian market. Mesulide, Nimesil and Nimesulide are sold in the form of a powder that is mixed with water. The resulting suspension provides immediate action. The imported drug Nimulid is produced in the form of simple tablets and capsules for resorption.
The main component of Diclofenac is diclofenac sodium. The medicine has strong anti-inflammatory, analgesic and antipyretic properties. Ketonal, Ketorol, Ketanov contain ketoprofen, an effective analgesic. The analgesic effect is individual for each person. Ketanov helps some, and Nise helps others.
No-spa and Drotaverine of the same action are considered effective antispasmodics. 15 minutes after taking the first tablet, the pain subsides. During menstruation, Spazmalgon is prescribed. It is an analgesic for urinary tract diseases and intestinal colic. Take 1-2 tablets up to three times a day. There are also a number of contraindications and side effects.
Tempalgin is suitable for many women. It does not cause allergies and copes well with pain. This is a non-narcotic drug, but it is advisable to take it with the permission of a doctor and strictly adhere to the dosage. Hormonal contraceptives also relieve pain. We are talking about regularly taking birth control pills.
The use of Frauplast adhesive is becoming popular. The German drug reduces pain during the menstrual cycle. Its action is based on the release of heat as a result of the interaction of components. In the first days of the cycle, the pain is more intense, so it is attached at the very beginning. The generated heat relieves spasm of blood vessels and muscles. The woman feels comfortable. The maximum heating temperature is 60 degrees. There are contraindications. Cannot be used for more than 12 hours.
Analogs based on paracetamol and ibuprofen are effective for reducing fever. They have fewer contraindications and are therefore approved for use by pregnant, lactating women and young children.
Doctors call painful menstruation dysmenorrhea. This problem affects many representatives of the fair sex. Every woman takes analgesic tablets at least once a month when symptoms increase and interfere with normal life. A large selection of drugs is available in the pharmacy chain. A distinctive feature is the different composition, manufacturer and duration of action. Nise has proven itself positively among consumers. However, the tablets have contraindications and side effects. You can drink Nise during menstruation only in extreme cases, when the pain does not go away.
Can Nise be taken as a pain reliever during menstruation? This question is asked by many women, since during menstruation the most painful and sometimes unbearable sensation is discomfort in the lower abdomen and lower back.
Surely all representatives of the fair sex have their own secrets for eliminating such pain. One of them is taking non-steroidal anti-inflammatory drugs. And this is not surprising, because such medications can eliminate not only discomfort in the lower abdomen, but also other signs of PMS.
Analogs
To improve the pain syndrome, you can use analogues of the drug Nise, which are not inferior to it in effectiveness. Other period pills:
- Actasulide is the most common analogue, similar in composition. Thanks to nimesulide, which is included in the composition, it is also effective for the treatment of pain during menstruation.
- Diclofenac – the main component of the drug is diclofenac sodium. The medication has strong anti-inflammatory, analgesic, and antipyretic properties. The peculiarity of this analogue is the absence of side effects.
- Ketonal - the main component is ketoprofen, which has strong analgesic properties. Sometimes Ketonal demonstrates greater effectiveness than Nise, but it is extremely rarely sold without a doctor’s prescription.
Nise is an extremely effective remedy for treating unpleasant menstrual symptoms. However, it is not recommended to use this medication on your own without the prescription and supervision of a specialist.
Composition, form
The drug "Nise" is used quite often during menstruation. It should be noted that this medication has two forms of release:
During critical days, only the oral form of the drug is allowed to be used.
According to the instructions, Nise tablets contain an active component such as nimesulide. This drug also contains calcium hydrogen phosphate, magnesium stearate, talc, cellulose, corn starch, silicon dioxide and sodium carboxymethyl starch.
Nise. Composition of the drug, active substance
The medicine Nise is produced in the form of dispersing tablets in cardboard packaging, where you can also find instructions with a detailed description of the medicine and what it helps with.
The main active ingredient of the drug is nimesulide , which determines the wide range of action of this drug, as it has clearly defined anti-inflammatory, antipyretic and analgesic properties.
Nimesulide prevents the formation of prostaglandins, which cause an inflammatory effect and also contribute to the development of edema.
Nimesulide is a chemical compound
Its amount per tablet can be 50 or 100 mg.
In addition to the active substance, the drug contains a number of other components:
- calcium orthophosphate;
- starch;
- sodium carboxymethyl starch;
- microcrystalline cellulose;
- magnesium stearate;
- pyrogenic silicon dioxide;
- talc;
- flavoring additives.
Properties of the drug
Nise tablets are used very often for menstrual pain. What is this connected with?
Experts explain this popularity of the drug by its following features:
- Able to reduce prostaglandin levels. As is known, such substances, found in large quantities in a woman’s body, cause strong uterine contractions. But they are the ones that sometimes lead to unbearable pain. The Naiza tablet taken during menstruation can significantly reduce the concentration of prostaglandins in the blood, as a result of which the discomfort in the lower abdomen disappears very soon.
- Reduced histamine levels. This process in the human body helps get rid of excess fluid, which, by the way, can also cause pain during menstruation. Thus, Nise tablets during menstruation can equally successfully eliminate not only discomfort in the stomach, but also in the lower back and head.
- Preventing the formation of free radicals in the human body. Thanks to its composition, the drug in question is capable of providing an antioxidant effect, which also makes it possible to eliminate discomfort in the stomach, as well as improve the overall well-being of a woman.
- Interaction with glucocorticoid receptors. This property of nimesulide, together with the inhibition of prostaglandin production, gives the medication anti-inflammatory properties. Therefore, if during menstruation a woman’s chronic gynecological disease worsens, then Nise tablets can easily solve this problem.
Indicated NSAID
As it was clarified above, the drug “Nise” can be taken during menstruation. However, it should immediately be noted that this medication is actively used for other diseases. The instructions indicate the following indications for use:
- rheumatoid arthritis;
- tendinitis, myositis;
- osteoarthritis;
- gouty and psoriatic arthritis;
- osteochondrosis;
- pain syndromes due to injuries, thrombophlebitis, in the postoperative period, gynecological diseases;
- fever of various origins;
- toothache and headache.
Nise tablets: indications for use
What Nise tablets help with is explained in detail by the instructions for this drug.
The instructions or your therapist will tell you what to take Nise tablets for.
Due to its wide spectrum of action, the drug is recommended for use for many diseases and health problems:
- rheumatic joint damage;
- arthritis of various origins;
- acute manifestations of gout;
- muscle, joint and lumbar pain;
- radiculitis;
- osteochondrosis;
- bursitis (inflammation of mucous bursae);
- inflammatory phenomena of various etiologies;
- elevated temperature;
- various pain syndromes.
Contraindications for NSAIDs
Is it possible to drink Nise for menstrual pain? It is allowed to take such a drug during menstruation, but it should be taken into account that this medication has certain contraindications.
According to the instructions, it is forbidden to drink the mentioned medicine if a woman has the following pathological conditions:
- bleeding disorders;
- intolerance to the components of the tablets (active and inactive substances);
- intestinal infection, enterocolitis;
- bronchial asthma;
- allergy to acetylsalicylic acid;
- liver diseases;
- gastritis or stomach ulcer;
- renal failure;
- heart disease, as well as the recovery period after surgery on it.
It should be especially noted that the drug “Nise” is prohibited for use by pregnant and lactating women, since its active component can negatively affect the fetus and newborn child.
This medicine should be prescribed with extreme caution when:
- diabetes mellitus;
- coronary heart disease;
- peripheral arterial diseases.
If your health suddenly deteriorates after taking the pills, you should immediately consult a doctor.
How to take the drug?
Women almost always take Nise tablets during menstruation without first consulting a doctor. In this case, experts recommend carefully studying the attached instructions. This is necessary in order to avoid the development of undesirable effects, since the medication in question has a fairly impressive list of side effects and contraindications for use.
So how much should you take Nise tablets during menstrual periods to reduce pain? According to the instructions, the therapeutic effect of using this drug occurs after taking two tablets per day. To avoid side effects, they should be taken at different times of the day, but only before meals. The tablet can first be crushed and then mixed with plain water.
In case of severe pain, it is allowed to take two doses at once (for example, in the morning or afternoon), and repeat in the evening. In this case, you need to monitor your condition.
Nise. Dosage of the drug
According to the official description, this drug should be used after meals to minimize irritant effects on the gastrointestinal tract. It is recommended to dilute the tablet in 5 ml of plain water until completely dissolved and consume it with liquid.
For adults and children over 12 years of age, the drug must be taken 1-2 tablets at a dosage of 50 mg at a time, twice a day. In this case, the daily amount of the drug should not exceed 400 mg.
Children under 12 years of age should not use the product in tablet form.
The duration of use of Nise tablets is determined by the attending physician, depending on what the drug is taken, individual symptoms and characteristics of the body.
However, the manufacturer does not recommend taking the medication for longer than 10 days, since long-term use significantly increases the likelihood of side effects.
Side effects
Experts often remind you that you should not mindlessly take the drug “Nise” for menstrual pain. What is the reason for this warning? Despite the fact that this medicine is good at eliminating discomfort, taking it in the maximum permitted dosage during the entire period of critical days may have an undesirable effect. By the way, sometimes side effects occur even with a minimum number of tablets. This usually happens if a woman has a special sensitivity to the components of the medicine.
Among the side effects of the drug "Nise" are the following:
- profuse sweating;
- skin rashes accompanied by itching;
- stomatitis, bleeding gums;
- anxiety, increased nervousness;
- dizziness and drowsiness;
- exacerbation of bronchial asthma, difficulty breathing;
- swelling, reduced urination;
- nausea, intestinal upset, vomiting;
- pain in the liver, bitterness in the mouth;
- weakness, lethargy, malaise;
- blurred vision.
