Immunomodulatory agent Selvim Galavit Sublingual tablets

Galavit and coronavirus (COVID-19). Galavit does not have a direct antiviral effect, that is, the drug does not directly affect the coronavirus. The mechanism of action of Galavit is implemented in indirect ways: the drug makes the immune system response optimal, avoiding excessiveness (cytokine storm). In the case of coronavirus infection (COVID-19), Galavit should be of great benefit, when taken early, preventing the development of severe forms of any infectious disease. Galavit gently reduces the overall inflammatory response in the body and reduces elevated body temperature, which makes the use of NSAIDs (ibuprofen, paracetamol, etc.) unnecessary. Thanks to the stimulation of phagocytosis, Galavit also makes it unnecessary to prescribe antibiotics for COVID-19, which still do not act on the virus and are prescribed more just in case. This leads to the emergence of antibiotic-resistant strains of bacteria.

It is best to start taking Galavit from the first day of the suspected coronavirus infection; in this case, COVID-19 or other respiratory infection should proceed easily, without high fever or complications. If the treatment was started later, at the stage of coronavirus pneumonia, then the temperature should drop and the patient should gradually recover. The more severe the patient’s condition, the more noticeable the effect of Galavit.

What is the drug

To understand whether Galavit can be used to prevent coronavirus, let’s consider the general purpose and features of the drug. It belongs to the pharmacological group of immunomodulators and exhibits an effective effect in shaping the body’s immune response to a viral infection and normalizes the formation of antibodies.

The main active ingredient is sodium aminodihydrophthalazindione. This compound has proven its ability to stimulate the functional and metabolic activity of the body’s immune cells (both innate and adaptive immunity) against viruses of various etiologies.

Additional components of the composition are sorbitol, lactose, calcium stearate, starch, menthol. The drug is available in the form of sublingual tablets, as well as in the form of rectal suppositories.

Galavit for ovarian cyst reviews

I recently wrote a review about how I went for an ultrasound at a medical center (Russia, Novosibirsk) and at the second ultrasound I was questioned about endometriosis. Moreover, how the diagnosis was made simply killed me, but you can read about this in the review about the center.

To which my doctor said not to be upset and prescribed me treatment with two drugs, one of which was immunomodulating anti-inflammatory rectal suppositories Galavit from Selvim. I’ll write about the second drug a little later.

To be honest, I don’t perceive suppositories as a drug for treatment at all and I think that it is better to give an injection or eat a pill. Well, the doctor, whom I trust, ordered me to do everything as he ordered.

General information

Galavit® Suppositories (instructions) Trade name Galavit®

INN or group name Aminodihydrophthalazindione sodium

Chemical name 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione sodium salt

Dosage form Rectal suppositories

Composition Active substance - sodium aminodihydrophthalazindione (Galavita) 100 mg; excipients - vitepsol W-35 (fatty acid glycerides) - 575 mg, vitepsol H-15 (fatty acid glycerides) - 575 mg.

Description Suppositories from white to white with a yellowish tint, torpedo-shaped without visible inclusions on the longitudinal section.

Pharmacotherapeutic group Immunomodulatory and anti-inflammatory agent.

ATX code L03, G02

Pharmacological properties The mechanism of action of the drug is associated with the ability to influence the functional and metabolic activity of macrophages. In inflammatory diseases, the drug reversibly inhibits for 6-8 hours the excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species by hyperactivated macrophages, which determine the degree of inflammatory reactions, their cyclicity, as well as the severity of intoxication. Normalization of the functional state of macrophages leads to the restoration of the antigen-presenting and regulatory functions of macrophages and a decrease in the level of autoaggression. Stimulates the bactericidal activity of neutrophil granulocytes, enhancing phagocytosis and increasing the body's nonspecific resistance to infectious diseases.

Pharmacokinetics Excreted from the body mainly through the kidneys. After rectal administration, the half-life is 40-60 minutes. The main pharmacological effects are observed within 72 hours.

Russia, 123290, Moscow, dead end Magistralny 1st, 5A, room. 91

Indications for use

As an immunomodulatory and anti-inflammatory agent in the complex therapy of immunodeficiency conditions in adults and adolescents over 12 years of age:

• infectious intestinal diseases accompanied by intoxication and/or diarrhea
• peptic ulcer of the stomach and duodenum
• viral hepatitis
• chronic recurrent diseases caused by the herpes virus
• diseases caused by human papillomavirus
• infectious and inflammatory urogenital diseases (urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis, acute and chronic salpingoophoritis, endometritis)
• purulent-inflammatory diseases of the pelvic organs
• postoperative rehabilitation of patients with uterine fibroids
• complications of the postoperative period in women of reproductive age
• purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy)
• postoperative purulent-septic complications and their prevention (including in cancer patients)
• chronic recurrent furunculosis, erysipelas
• asthenic conditions, neurotic and somatoform disorders, decreased physical performance (including in athletes); mental, behavioral and post-withdrawal disorders in alcohol and drug addiction
• inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases
• frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent ARVI, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) and their prevention

GALAVIT (suppositories)

Look online to see where you can find it cheaper.
Which is exactly what I did. Yes, treatment is not cheap at all now, so you just need to not get sick. I don't think there's anything wrong with my immune system. But as a last resort, it would be better to take Immunal tablets, or at least in drops. Of course, they don’t cost a penny, but still not that much money. And an even better remedy for me is the herbal tea Health+ “Echinacea”. But the party said it was necessary, and there was nothing to be done; I had to buy it.

Moreover, after reading positive reviews about these suppositories and the drug, I realized that there was nothing wrong with boosting immunity, so I went and bathed them.

This is what a package of 10 suppositories looks like, each suppository is 100 mg. This one and 5 more 100 mg suppositories are sold in pharmacies.

Should I say that I felt my inflammatory process? No, everything was as usual for me, and what doctors had previously considered normal for my body became a problem this time. Moreover, we are now puzzled by the question of the second child. And yet, I think it’s all because of this that the doctor prescribed me a course of these suppositories.

There is an alphabet for the blind on the box, which I think is absolutely correct. As I said, I was looking for slightly cheaper Galavit candles and found ten of them for 794 rubles. The candles have a shelf life of three years. This is what the candles themselves look like. In general, ordinary candles are no different from others in appearance. The instructions for use describe the pharmacological properties of this drug.

But the range of applications of this drug is very wide, ranging from viral diseases such as hepatitis, herpes and other purulent inflammatory diseases of the pelvic organs and not only, they are also used for the rehabilitation of fibroids, after operations. And so for inflammatory processes of the throat, mouth and colds.

In general, whatever one may say, a very useful drug.

Do not take during pregnancy and lactation or if there is an individual intolerance to the components of the medicine.

Taking suppositories depends on what exactly you are treating. The doctor prescribed me 15 days every other day. It should be borne in mind that when taking other medications, this drug reduces the dose of antibiotics.

Side effects can only occur if you are allergic to the components. Therefore, there is nothing wrong when you take the drug. But there was no super surge of strength either. Common days.

But on the other hand, I understand that there is nothing wrong with helping your body, but you still need to be more careful. Because it arrives somewhere and departs somewhere. Still like on the scales. Therefore, after a course of treatment with this drug, immunity may decrease and you may catch a cold. True, I had nothing like that. The drug is produced in Moscow by the company Selvim.

As for the reception, I can’t say that it was pleasant. Nothing like that, but I don’t like this form of release of this medicine the most; injections are better.

On my own behalf, I can recommend Galavit, as it helps our body. But of course the price doesn’t make him too happy. Because of this, I will give this drug a 4.

Directions for use and doses

Rectally. The suppository is released from the contour packaging and then inserted into the rectum. It is recommended to empty the intestines first. The dose and duration of use of the drug depends on the nature, severity and duration of the disease.

• For acute infectious intestinal diseases accompanied by diarrhea syndrome: the initial dose is 2 suppositories once, then 1 suppository 2 times a day until the symptoms of intoxication are relieved. It is possible to subsequently continue the course of 1 suppository with an interval of 72 hours. A course of 20-25 suppositories.
• For gastric and duodenal ulcers in the acute period: 2 days, 2 suppositories once a day, then 1 suppository at intervals of 72 hours. A course of 15-25 suppositories. In the chronic period: 5 days, 1 suppository once a day, then one suppository every 72 hours. Course of 20 suppositories.
• For viral hepatitis: the initial dose is 2 suppositories once, then one suppository 2 times a day until the symptoms of intoxication and inflammation subside. Subsequent continuation of the course of 1 suppository with an interval of 72 hours. Course 20 -25 suppositories.
• For chronic recurrent diseases caused by the herpes virus: 1 suppository daily - 5 suppositories, then one every other day - 15 suppositories.
• For diseases caused by the papilloma virus: 5 days, 1 suppository once a day, then one suppository every other day. Course – 20 suppositories.
• For urogenital diseases - urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis: 1 day, 1 suppository twice, then one suppository every other day. A course of 10-15 suppositories (depending on the severity of the pathological process).
• For salpingoophoritis, endometritis in the acute period: 2 days, 2 suppositories once a day, then one at an interval of 72 hours. In the chronic period: 5 days, 1 suppository once a day, then one every 72 hours. Course - 20 suppositories.
• For acute and chronic purulent diseases of the pelvic organs - in the acute period: 1 day, 2 suppositories once, 3 days, one suppository daily, then one every other day for 5 days. Course - 10 suppositories. In the chronic period: 5 days, 1 suppository once a day, then one every 72 hours. Course - 20 suppositories.
• For postoperative rehabilitation of patients with uterine fibroids and complications of the postoperative period in women of reproductive age: 5 days, 1 suppository once a day, then one suppository every other day. Course - 15 suppositories.
• For the prevention and treatment of surgical complications in the pre- and postoperative period (including in cancer patients): 1 suppository is prescribed once a day - 5 suppositories before surgery, 5 after surgery, one every other day and 5 suppositories at intervals 72 hours. In severe cases of the disease, the initial dose is 2 suppositories once or 2 times a day, one at a time. Course - 20 suppositories.
• For chronic recurrent furunculosis, erysipelas: 5 days, one suppository once a day, then one suppository every other day. Course - 20 suppositories.
• For asthenic conditions, neurotic and somatoform disorders, for mental, behavioral and post-abstinence disorders, in patients with alcohol and drug addiction: 5 days, one suppository daily, then one suppository every 72 hours. A course of 15-20 suppositories. To increase physical performance: 1 suppository every other day – 5 suppositories, then one suppository after 72 hours, course – up to 20 suppositories.
• For inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases: initial dose of 1 suppository daily - 5 suppositories, then one at an interval of 72 hours. Course 15 suppositories.
• For nonspecific prevention and treatment of influenza and acute respiratory infections, one suppository 1 time per day. Course 5 days.

Pharmacological properties and composition

The active component of the drug is sodium aminodihydrophthalazindione. This is a substance of synthetic origin that has anti-inflammatory and immunomodulatory effects. Depending on the form of release, the composition also contains other auxiliary components. The effectiveness of the drug is as follows:

1. The function of cells that neutralize and absorb pathogenic microflora and harmful substances is activated.
2. The production of cytokines - compounds that are responsible for the development of inflammatory processes - improves.
3. The production of interferons increases, thanks to which the body better resists infections of various origins.
4. The number of antibodies against a particular pathogen increases.

The drug is mainly excreted through the kidneys. The effect of use can last for 3 days.

Use of GALAVIT for acute inflammation of the uterine appendages

A survey of 45 women with FFM aged 17–38 years was conducted. The control group consisted of 11 healthy women. All patients with ABPM at the initial visit complained of pain in the lower abdomen, the duration of which varied from one day to 3 months, increased body temperature to low-grade and febrile, general weakness, and decreased performance. Discharges from the genital tract of patients with OVPO were of a different nature - from sanguineous to mucopurulent with an unpleasant odor. Previous inpatient treatment for endometritis and salpingoophoritis was carried out in 34 (75.5%) patients. During vaginal examination, thickened, painful uterine appendages were palpated in all patients. An ultrasound scan did not reveal any volumetric pathological formations of the uterus, ovaries or fallopian tubes. In a clinical blood test, only 13 women showed an increase in the total content of blood leukocytes and ESR. A biochemical blood test and clinical urine test did not reveal any abnormalities.

When diagnosing sexually transmitted infections, the following pathogens were identified in various combinations: Chlamydia trachomatis

- 9%,
Candida albicans
- 23%,
Ureaplasma urealiticum
- 15%,
Human papillomavirus
- 5%,
Hepres simplex
- 66%,
Cytomegalovirus hominis
- 9%,
Toxoplasma gondii
- 3%. Bacterial vaginosis was found in 40% of patients.

In the acute phase of inflammation of the uterine appendages, a decrease in the activity of the cellular component of immunity was found in 18 (40.0%) patients. The detected decrease in the immunoregulatory (CD4/CD8+) and phagocytic index, as well as the total number and percentage of cytotoxic cells in the acute phase of inflammation in all subjects, regardless of the phase of the menstrual cycle, indicated a weakening of antiviral immunity and correlated with a low level of NK cells (CD16), which is typical for a viral infection. The disruption of the functional activity of the cellular component of immunity can be explained by the presence in the body of patients of a persistent viral infection, which leads to a decrease in the number of T-suppressors and inhibition of the antiviral activity of the body. The decrease in the total number of NK cells, as well as the number of phagocytic cells, is likely caused by the development of secondary bacterial infections.

High levels of circulating immune complexes (CIC), a decrease in the bactericidal properties of neutrophils, as well as the phagocytic index of microbial bodies and the absolute phagocytic index of microbial bodies were revealed, which required increasing the functional activity of neutrophils using immunocorrection.

The increased level of pro-inflammatory cytokines (interleukins IL-6, IL-8, IL-1-β, tumor necrosis factor TNF-α, granulocyte colony-stimulating factor GCSF, etc.) made it possible to judge the duration, extent of spread and severity of the inflammatory process. When studying the indicators of humoral immunity, a significant decrease in the level of serum IgA (1.75±0.15) was observed in 7 (15.5%) patients, which may indicate that the inflammatory process is older. The level of serum IgG in 7 (15.5%) patients was increased and amounted to 17.85±3.28 g/l, in 3 (6.67%) it was decreased (10.3±0.78 g/l), which could indicate immunodeficiency. In 9 (20.0%) patients, an increase in the level of serum IgM (3.75±1.43 g/l) was diagnosed. In 3 (6.67%) patients, a decrease in the level of serum IgM was observed (1.13±0.08 g/l), which may also indicate immunodeficiency.

In some patients, both a decrease in the amount of one of the immunoglobulins and an increase in the other were observed. Therefore, it is extremely difficult to judge the degree of immune system disorders based on the quantitative indicator of immunoglobulins. When studying the cytokine status in 43 (95.5%) patients with ABPM, a persistent decrease in the production of α- and γ-interferons (IFN) by blood cells was noted by almost two times.

Immunocorrection was carried out with the drug GALAVIT, which has anti-inflammatory and immunomodulatory properties, which are caused by the activation of immunocompetent cells and the inhibition of pro-inflammatory blood cytokines. GALAVIT was administered to 29 patients with acute renal failure according to the following regimen: 100 mg intramuscularly for 10–15 days. The remaining 19 patients with ARVO made up the comparison group. All patients received complex therapy, including antimicrobial (cephalosporins, fluoroquinolones, imidazole derivatives, polyenes) and non-steroidal anti-inflammatory drugs.

After treatment with GALAVIT, in 22 (75.8%) patients, the level of leukocyte α-IFN normalized, and the level of γ-IFN increased by 65% ​​from the initial values. Against the background of complex immunotherapy, the level of α-IFN normalized in 21 women, increased by 75% of the initial values ​​in 3, by 50% in 3, and by 30% in 2.

One month after treatment with GALAVIT, the total number of cytotoxic T-lymphocytes (CD8+) in 9 (31.3%) patients was restored to physiological values ​​compared to the control group (healthy women). At the same time, activation of neutrophils, an increase in the phagocytic index and phagocytic number of microbial bodies, as well as the level of activated T-lymphocytes were noted. Restoration of absolute and relative indicators of mature B-lymphocytes was found in 11 (37.9%) women. The immunoregulatory index (CD4/CD8+) returned to normal in 14 (48.3%) patients. A predominance of levels of anti-inflammatory cytokines in the blood (IL-4, IL-10) was revealed, while the level of production in the blood serum of IL-1, IL-6 and TNF-α decreased slightly, which also correlated with a decrease in IgG titers and the disappearance of clinical manifestations inflammatory process. The onset of a period of remission and the absence of acute inflammation in all subjects of the main group was confirmed by a gradual decrease in the level of serum IgM.

Indicators of immune status tended towards positive dynamics in only 16 patients who received treatment according to the generally accepted regimen without immunotherapy. At the same time, they did not experience a decrease in the level of serum immunoglobulins (IgM), the absolute indicator of phagocytosis (phagocytic index of microbial bodies) did not change, and interferon status remained at the same level. As the results of our studies have shown, patients with AFPV are characterized by a Th-1 type of immune response due to an increase in the relative number of CD4 lymphocytes and suppression of local immune functions due to a decrease in the expression of adhesion molecules. When studying the cytokine status, the inflammatory cytokines GCSF, IL-6, IL-8, the levels of which are comparable both in blood serum and biological fluids, are pathognomonic for patients with ARVOM.

Thus, the study of all parts of the immune system makes it possible to determine the degree of anti-inflammatory, antiviral, antiproliferative activity of endogenous cytokines, the processes of their interaction with other immunocompetent cells, as well as to predict the course and outcome of FFM. The study proved the high clinical effectiveness of the drug GALAVIT, which has an anti-inflammatory, immunomodulatory effect aimed at restoring the main components of the immune system.

o

A.N. Strizhakov, Academician of the Russian Academy of Medical Sciences, A.I. Davydov, professor, doctor of medical sciences, Zh.A. Kagramanova, Candidate of Medical Sciences, Moscow Medical Academy named after. I.I. Sechenov

Release form

The product has 3 dosage forms: powder for injection, tablets, rectal suppositories, each of them has its own characteristics. Thus, Galavit in powder is sold in bottles of 50 and 100 mg. One bottle is the daily dose for patients of different ages. The powder is used to prepare a solution.

tablet form not so long ago. They have a dosage of 25 mg and are intended for resorption. The tablets contain menthol extract and are sold in packs of 10 pieces.

suppositories are prescribed to patients of all ages. The dosage can be the same as that of the powder - 50 and 100 mg. The suppositories are intended for rectal administration.

Instructions for use of Galavit (Method and dosage)

If the patient uses Galavit suppositories, the instructions must be strictly followed. Different forms of the drug can also be used: injections, tablets, suppositories.

Suppositories are intended for rectal use. Before using the product, you need to wash your hands, remove the suppository from the shell and carefully insert it into the rectum. Before administering the drug, it is advisable to empty the intestines. The dosage and duration of therapy is determined taking into account the nature of the disease. One suppository contains 0.1 g of active substance.

For infectious diseases , as a rule, the initial dosage is 0.2 g, after which 0.1 g is administered 2-3 times daily until all signs of the disease are eliminated. Next, Galavit is administered in a dose of 0.1 g once every three days. No more than 25 suppositories are used per course.

For diseases of the genitourinary and gastrointestinal tract, 0.2 g of medicine is administered once a day for two days. Next, 0.1 g of the product is administered once every three days. 15-25 suppositories are used per course.

For benign prostate hyperplasia uterine fibroids , it is practiced to administer 0.1 g of drugs once a day for 5 days. Next, a dose of 0.1 g is used once every three days. No more than 20 suppositories are used per course.

In order to prevent complications after surgical interventions, 0.1 g of the drug is administered before and after surgery once every five days. Next, 0.1 g of the drug is used once every two days for ten days. Subsequent maintenance therapy involves the use of 0.1 g of the drug once every 72 hours. No more than 15 suppositories are used per course.

For skin diseases, initially 0.1 g of the drug is used once a day for five days, then 0.1 g of the drug is administered once every two days. No more than 20 suppositories are used per course.

For herpes , 0.1 g of Galavit is used once a day for 10 days, after which 0.1 g is administered once every two days. No more than 25 suppositories are used per course.

When treating chronic inflammation caused by immunodeficiency , it is used to treat 0.1 g once every three days or 0.1 g of Galavit once a day for five days. Next, the practice is to administer 0.1 g of the product once every 48-72 hours. No more than 20 suppositories are used per course.

In order to strengthen the immune system in patients with cancer, an initial dose of 0.1 g is prescribed once every two days for 10 days, later it is practiced to administer 0.1 g of the drug once every three days. 20-30 suppositories are used per course.

When prescribing Galavit in the form of injections, the powder must initially be dissolved in 2 ml of water for injection or 0.9% sodium chloride. The prepared solution is administered intramuscularly. The dosage, treatment regimen, as well as its duration are determined depending on the course of the disease and its characteristics. As a rule, the general course of therapy includes 15-30 injections.

Ichthyol candles and their features

You can often hear that excellent results in the treatment of cysts can be achieved with the help of ichthyol. This substance is frighteningly black in color. It is obtained from shale resins. The unique composition includes more than 10% natural sulfur. The use of the drug guarantees the elimination of pathological processes in the pelvic organs. Ichthyol suppositories have been used in gynecology for diseases of the female reproductive system for more than a century. Despite the fact that the modern pharmaceutical market is rich in other, more modern, drugs, these suppositories hold the leading position in sales.

Ichthyol suppositories for ovarian cysts are inserted into the rectum. Vaginal use can lead to serious problems and complications. After 3-4 rectal injections, you can notice the following effect:

• the source of inflammation is eliminated;
• blood circulation is normalized;
• pain syndrome decreases.

Before administering suppositories, you need to cleanse the intestines. Place candles three times a day. The duration of therapy is determined by the doctor.

The drug cannot be combined with drugs based on iodine, heavy metal salts and alkaloids.

Ichthyol rarely causes adverse reactions. In exceptional cases, itching and rashes on the body are possible.

Directions for use and dosage

Before you start using the medicine Galavit, you must consult your doctor and carefully read the instructions for use. The manufacturer produces the medicine in different forms: suppositories, tablets and powder, so dosages for all forms are given below. Galavit suppositories are administered rectally. Before using the product, it is necessary to cleanse the intestines with an enema, followed by hygiene of the anus. Before administration, remove the suppository from the protective packaging, take a lying position and bend your knees. Carefully introduce the product as deeply as possible. Use of the tablet form is sublingual. Galavit solution is prepared as follows: the drug must be diluted in two milliliters of water for injection. Ulcerative disease.

• Suppositories: initially, 2 suppositories once a day for a two-day period, after that 1 suppository every 72 hours, the length of the therapeutic course is twenty suppositories.
• Tablets: initial two-day period - 1 tablet four times a day, then 1 tablet four times a day, at 72-hour intervals, duration of therapy is about 21 days.
• Solution: initial two - 200 mg once a day, then injection of 100 mg every 72 hours.

Viral hepatitis disease.

• Suppositories: initial dosage: 2 suppositories once, then 1 suppository twice a day, until intoxication symptoms disappear, then 1 suppository at 72-hour intervals, course length - about 25 suppositories.
• Tablet form: initial dose: 2 tablets twice a day, until the intoxication effects disappear, after which the drug should be used in a dosage of 1 tablet - 4 r. per day with a frequency of once every three days, for a period of twenty-one days.
• Solution: initial single dose - 200 ml, then 100 mg should be administered twice a day until the intoxication effects disappear, after which 100 mg should be administered daily, once every three days. The duration of the course is about 25 introductions.

Diseases in the pelvic area.

• Suppositories: the initial single dosage is 2 suppositories, in the subsequent three-day period one suppository is prescribed daily, followed by a single use of a suppository every other day for a five-day period. The duration of the course is 10 suppositories.
• Tablet form: initial use: 2 tablets twice a day, then over a three-day period, 1 tablet four times a day, then 1 tablet 4 times a day, with an interval of 48 hours, then 1 tablet four times a day, with an interval of 92 hours. The duration of the therapeutic course is about twenty-one days.
• Solution: initial dose 200 mg once. Next, the medication is administered for three days in a row at 100 mg, then for five days it is necessary to administer 100 mg of the drug every other day. Therapy lasts 20 injections.

Acute respiratory viral infections and other recurrent diseases of the respiratory system.

• Candles: 1 candle once a day, for a five-day period.
• Tablet form: for a five-day period, use 1 tablet four times a day, then for two weeks, 1 tablet four times a day, every other day.
• Solution: 100 mg daily for 5 days, then 100 mg every other day for two weeks.

Papillomavirus.

• Candles: over a five-day period, 1 candle is prescribed once a day, then 1 candle every other day. The duration of therapy is about 20 suppositories.
• Tablet form: over a five-day period, 1 tablet is prescribed four times a day, then 1 tablet four times a day every other day. The duration of therapy is about three weeks.
• Solution: over a five-day period, injections of 100 mg once a day are prescribed, then 100 mg every other day for a two-week period. The duration of therapy is 20 injections.

Urogenital diseases.

• Suppositories: the initial dose is 1 suppository twice a day, then 1 suppository is used every other day. The duration of therapy is about 15 suppositories.
• Tablet form: the initial dose is 2 tablets twice a day, then 1 tablet four times a day every other day, for a two-week period.
• Solution: The initial dose is 200 mg per day and is divided into two injections. Next, the drug is used at a dose of 100 mg every other day, the therapeutic course is 10 - 15 administrations.

For other diseases, the dosage and length of the therapeutic course are prescribed by the attending physician.

Use during pregnancy and breastfeeding

The drug is contraindicated during pregnancy and lactation.

Use in children

The drug is prescribed to children over 6 years of age.

special instructions

When used simultaneously with antibiotics, it is possible to reduce the course doses of the latter

Immunomodulatory agent Selvim Galavit Sublingual tablets

Hi all!

After two years of fighting bacterial acute respiratory viral infections, green snot and sore throats in myself and my child, I already have some experience and knowledge in their treatment, and I want to share my thoughts with you.

There are immunostimulants on the market that stimulate the immune system, and there are immunomodulators that modulate the immune system, that is, they raise it where it is weak and do not touch it where it is normal.

Our first immunostimulant was IRS-19, based on bacterial lysates, it did not help us cope with bacteria in the nose, where did they come from, I wrote everything in this review.

I repeat, the child developed green snot after he went to kindergarten, he had white snot, and we washed him in the bathhouse. After that, he has green snot every month or two. The bath provoked the growth of bacteria. I became infected from him when I blew my nose into his handkerchief (I still don’t understand why I did this myself). I also started having tonsillitis in addition to sinusitis, but the child did not have tonsillitis. We lived like that, constantly drinking antibiotics.

On this site I learned about the drug Galavit, it is an immunomodulator, but to be honest, I don’t fully understand how it works, how it can be done so as to raise only the weak link of the immune system and not touch the strong one.

Nevertheless, on the manufacturer’s website everything is described as if this drug is almost a panacea for all ills. I was particularly interested in ENT diseases and getting rid of repeated relapses of bacterial ARVI.

At that time, I really thought that an immunomodulator could boost immunity and then the body itself would cope with the bacterial infection in the nose and throat.

So I concluded that this was a mistake!!!!!

With regard to viruses, immunomodulators can help, since the virus lives inside the cell, we do not have medicines for viruses, since it is very difficult to kill the virus without killing the cell itself, so here we can only increase immunity, I actually had experience of curing the papilloma virus a long time ago person, the drug Isoprinosine helped me then (if anyone needs it).

But with regard to bacteria, there is a different treatment tactic. Only an antibiotic can kill bacteria. And only then, to avoid re-infection, you need to take immunomodulators, but you don’t need to hope that this alone will get rid of the infection.

An immunomodulator will not help kill a bacterial infection! Only antibiotics!

Therefore, we return to Galavit.

I bought the drug in the form of sublingual tablets, there is also a drug in the form of rectal suppositories and a solution for intramuscular use.

General information:

Name - Galavit

Purpose: immunomodulatory and anti-inflammatory agent

Form: sublingual tablets, 25 mg

Quantity - 20 tablets (there are 10 more tablets, this is for the prevention of ARVI and influenza)

Price - 413.30 rubles (link where to buy)

Active ingredient: Aminodioxotetrahydrophthalazinedione sodium

, Russia, Moscow.

Conditions for dispensing from pharmacies - without a prescription

Age of use: from 12 years

Galavit has a similar effect to Polyoxidonium. But they have different active ingredients. They have different pricing policies. Polyoxidonium is widely advertised, so the price is very high, but Galavit is not advertised and its price is humane. I needed 3 packs for the course, it cost about 1200 rubles. Polyoxidonium tablets would be much more expensive.

This is what the tablets look like. White, dissolves very easily under the tongue, almost immediately.

Indications for use: what’s not there! For every taste!

My most recent indication is frequent bacterial acute respiratory viral infections and ENT diseases.

Directions for use and dosage:

I took 1 tablet 4 times a day for 5 days, then 1 tablet 4 times a day every other day for a total of 10 days.

What effect did the pills have on me?

It’s difficult to judge, but in the end they only affected my throat, I didn’t have a repeat sore throat, but sinusitis appeared again, green snot again.

And again I had to take an antibiotic.

But there is an important point!!!!!

My child and I constantly drank the same antibiotic, I drank amoxicillin, and the pediatrician constantly prescribed him Augmentin.

This was the biggest mistake of our treatment! I have already written that only an antibiotic can kill an infection, but the main thing is to choose the right antibiotic.

Amoxicillin acts only on those bacteria that do not produce beta-lactamase, such antibiotics are called beta-lactam, but in our country, apparently, they produce it and are not killed by this antibiotic, since there is an exacerbation every month and you just need to change the antibiotic and that’s it.

I passed a culture test from the child’s nose, hemophilus influenzae and moraxella were cultured, and the ENT specialist prescribed him the antibiotic Klacid. It is a macrolide and kills bacteria that produce beta-lactamase.

The last time I took the antibiotic Azithromycin.

I tried to give the child some other dietary supplements to boost immunity. All this does not work, it only gave him an allergy, for which it took a long time to be treated. All these vitamins are all a sham, and he already turned out to be allergic to ascorbic acid.

My advice and my conclusion is that when treating bacterial acute respiratory viral infections, do not focus on immune agents, as I thought at first, you just need to look for the antibiotic that will definitely kill the infection. That's all.

The child has already taken Augmentin 4 times, what’s the point, after a month the snot is green again, which means the antibiotic needs to be changed, which means the bacteria are resistant to it and are not completely killed.

And only then, if the culture is clear, you can take immunomodulators to avoid getting infected again.

Although Galavit's instructions indicate that it can be used in conjunction with antibiotics.

It is possible, but if, as in my case, the antibiotic does not completely kill the infection, then Galavit will not save or help. I got sick again after taking amoxicillin and Galavit, because the bacteria were resistant to this antibiotic.

These are my conclusions. This is my experience. This is my personal opinion, if yours is different, then we just have different opinions.

But still, I advise you to try Galavit, maybe it will suit you and like it, everything is individual.

Update 03/10/2017

I'm cured! When I got sick again, I took the antibiotic Azithromycin and at the same time boosted my immunity with the drug TIMALIN.

Now I'm not sick.

Still, immunity can and should be raised simultaneously with antibiotic treatment, so you will prevent the development of future infection.

Galavit did not help me, only TIMALIN helped.

Galavit helps with coronavirus if taken for prevention

It is impossible to say for sure whether Galavit helps with coronavirus if it is taken to prevent infection. Such studies have not been conducted, the drug is not included in the group of promising ones, so one can only focus on its use in other acute viral diseases of the respiratory tract. To prevent them, 50 mg of the drug per day is prescribed for 5 days - 1 tablet twice a day or one 50 mg suppository at night.

Doctors using Galavit for preventive purposes may recommend another regimen - 1 tablet 2 times a day every 2 days, after a month of taking it you need to take a break for 2 weeks. Galavit for the prevention of coronavirus COVID-19 can be taken as a single remedy or in combination with zinc preparations, omega acids, and licorice root syrup. In any case, individual appointments are required.

What suppositories are effective for ovarian cysts

In most cases, the appearance of a capsule with liquid contents occurs due to an imbalance in hormone levels. To eliminate a functional neoplasm, it is enough to normalize the levels of estrogen and progesterone. For this purpose, doctors prescribe hormonal suppositories.

One of the most effective drugs is Utrozhestan. The medicine costs about 400-500 rubles.

Its active component is progesterone. After a few days, the woman will feel significant relief from symptoms. The full course is 10 days. During this time, the functional cyst can completely resolve.

If the cause of the tumor is inflammation, the doctor may prescribe Longidaza suppositories for ovarian cysts. The optimal daily dose and duration of treatment should be determined by a gynecologist. The price of the drug depends on the dosage and ranges from 1500 to 3000 rubles. The active substances of the medicine help resolve adhesions, stop purulent processes, remove blood clots and seals.

Galavit is often used in combination with this drug. The drug can be presented as tablets, rectal suppositories or injection solution. It has immunomodulatory and anti-inflammatory effects. The price of Galavit varies from 300 to 1000 rubles.

Precautionary measures

Since there is no guarantee that Galavit will protect against infection, in no case should you ignore the basic rules when taking it: washing your hands, using antiseptics, avoiding contact with others at a distance of up to a meter and for more than 10 minutes.

If any unusual symptoms appear while using Galavit, you should stop using it and immediately consult your doctor. An immediate call to emergency medical assistance is needed if the temperature rises to 39 degrees, shortness of breath increases, a feeling of tightness in the chest, or muscle pain. All these signs accompany extensive lung damage, swelling of the lung tissue and the development of respiratory failure.

Galavit has not yet been studied for coronavirus, and its effectiveness has not been fully proven for other viral infections. Due to the high risk of a new disease, admission is carried out only on the individual recommendation of a doctor.

Scientists' opinions and doctors' reviews about Galavit

Filatov Nikolay Nikolaevich

, Deputy Director of the Research Institute of Vaccines and Serums named after I. I. Mechnikov (Moscow), April 20, 2020 at a meeting on the sanitary and epidemiological situation in the Russian Federation:

There are many scientific studies that have proven the high effectiveness of Tamerit in these situations. This is a drug called “Galavit”. It had approved instructions for use and was approved for use for medical purposes. Now, however, these documents are already outdated. But scientific research has shown its high effectiveness. Perhaps it is now necessary to conduct an evaluation and, as part of a clinical trial, evaluate the effectiveness of this drug and, possibly, include it in the treatment regimen of patients.

Kolesov Sergey Vasilievich

, head of the department of spine pathology at the Central Research Institute of Traumatology and Orthopedics named after N. N. Priorov (Moscow) on April 24, 2021, addressed from his Instagram account:

Analogs

The drug has no direct analogues for the active component. If there is a need to replace it for one reason or another, according to a medical decision, you can take another form instead of the prescribed one. For example, if tablets were prescribed, they can be replaced with suppositories.

There are a large number of drugs available in pharmacies that have similar immunomodulatory properties, but most of them are expensive. Such drugs include Alokin alpha, Gepon, Immunomax, etc. In addition, children can be prescribed Anaferon for children, and adults Immunoflazid, Lavomax, Lynchi, Imunoplus, etc.