Klaira or Yarina - which is better? Advantages and disadvantages!

Pregnancy like Baba Yaga's, fake pregnancy (photo, my story and comparison with Yarina)

I’ll start with the fact that I took Yarina for 6 months.
and began to notice terrible swelling in my legs, as well as pressure jumps. After consulting with a doctor, we decided to stop taking the drug for a while and see if pressure was the cause. Here you can see a review of Yarina. After a 2-month break, the pressure did not normalize and the doctor suggested switching to a more gentle OC - Qlaira.

The first pack arrived just when I moved into my MCH. And then it began.

To be honest, Yarin’s reception left only a pleasant impression, so somehow it never occurred to me to expect anything else.

The first thing I didn’t like was that this is not a monophasic drug, that is: you cannot push back the red days of the calendar and if you miss some tablets from the pack you need to start a new one.

On the 2nd or 3rd day, a brown spot began. I was ready for this, the same thing happened with Yarina, BUT, sorry, it lasted a MONTH. We just got together, romantically, you know, but I, like a sewer pipe, keep leaking and leaking.

Then, even worse, for the first time in my life my PERIOD did not come. 1 DAY no arrival 2 DAY no 3 DAY no

After reading scary stories online about girls getting pregnant on OK, I really started to panic. I thought, what if I’m pregnant and taking this chemistry?

On the 4th day of the delay, I bought 3 different tests (I am very anxious and suspicious). All showed negative results and I didn’t calm down much.

I talked to the doctor and she said that it was normal that the endometrium in the uterus had not accumulated in sufficient quantities to exit. What's next? Everything will be great for a month.

Well, I lived quietly for another 21 days and then it began.

I had pimples all over my face that I've never had in my life.

Here's photo proof

Life has never been worse.

They were red, large, subcutaneous, like chiri.

I cried for probably 2 days and didn’t leave the house for another 3 or 4 days.

On the 24th day my periods arrived, normal, not heavy, without pain.

The acne lasted for 2 weeks and I was already eager to quit these pills.

But still reason won.

Bottom line

I went through 2 months of hell. Now I am taking 4 packs of Qlaira, there have been no more incidents. My periods come like clockwork, there were no more inflammations, I don’t see any side effects. My facial skin has improved. I'm still drinking them and have no plans to quit.

Compared to Yarina

I liked Yarina more, since the drug is monophasic, I could afford to postpone these days at sea, for example.

Also, getting used to Yarina was less painful for me, but this is purely individual.

And unlike Yarina, terrible reduces libido.

At the first opportunity I will switch to Yarin

Of the variety of modern contraceptives taken orally (oral contraceptives), Klaira and Yarina are often prescribed. Women trying to avoid unwanted pregnancy are interested in the safety and effectiveness of medications. Which pills work better, cause fewer side effects, and how to switch from one to the other?

Forms of release and methods of use of the product

There is only one form of release of the drug - tablets. Since it is combined, the package contains 26 multi-colored film-coated tablets (dark yellow, red, light yellow, dark red) and 2 white placebo tablets.

To monitor the daily intake of the product and ease of use, the blister of tablets comes with 7 strips with the names of the days of the week, which are recommended to be attached to the blister and follow the daily intake.

The drug is taken 1 tablet per day at the same time, regardless of meals, swallowed whole and washed down with a sufficient amount of clean water. It is not recommended to skip taking the medicine, and after finishing one package you should immediately start using the medicine from a new one.

Before using Claira during menopause, be sure to consult a specialist for diagnosis and adjustment of the method of use of the product.

Yarina and Klaira: comparison

Despite the fact that both drugs belong to the group of contraceptives, the difference between them is significant. The component composition and dosages differ, so in order to compare Yarina and Klayra, you need to carefully familiarize yourself with their main characteristics.

Compound

Yarina

Contains two main active ingredients:

• 3 mg drospirenone;
• 0.03 mg ethinyl estradiol.

Yarina Plus tablets additionally contain the vitamin calcium levomefolate.

Claira

It also consists of two active components - estradiol and dienogest. Their dosage in one tablet varies, as it depends on the day of the menstrual cycle. But in general, this drug contains fewer hormones.

Mechanism of action

Both drugs contain two types of active ingredients - estrogens and gestagens. Their main purpose is to suppress the maturation of an egg capable of fertilization by regulating hormonal levels. At the same time, the viscosity of the mucus in the cervical canal changes, which prevents the penetration of sperm.

Due to the stabilization of hormonal levels, a clear 28-day cycle is established, pain during menstruation disappears, and the volume of discharge decreases. In addition, the activity of the sebaceous glands is normalized (acne disappears, the general condition of the skin improves). Fat metabolism in cells is also optimized, and the amount of bad cholesterol is reduced.

Indications

The main and general indication for the use of Yarina and Qlaira is the prevention of unwanted pregnancy. However, Yarina is often prescribed also for:

• reducing swelling caused by hormonal imbalance;
• treatment of acne and seborrhea (a disease associated with increased production of sebum).

Contraindications

Common to Klaira and Yarina:

• predisposition to blockage of blood vessels by blood clots (thrombosis);
• precursors of thrombosis (narrowing of the coronary arteries - angina pectoris);
• the consequences of such a blockage - stroke or heart attack;
• drug intolerance;
• pregnancy;
• breast-feeding;
• benign and malignant tumors of the liver, genital organs, mammary glands;
• pancreatitis - inflammation of the pancreas;
• diabetes mellitus with vascular disorders;
• liver failure or disease;
• migraine – intense attacks of headache;
• bleeding from the vagina of unknown origin.

Yarina, in addition, should not be taken by smoking women over 35 years of age or by patients with renal failure.

Side effects

Impact on hormonal levels can lead to various side effects:

• nausea;
• mood swings;
• headache;
• decreased sex drive;
• enlargement and tenderness of the mammary glands;
• thrombosis (rare, but very dangerous).

Comparison of addiction in Yarina and Klaira

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Yarina is quite similar to the similar values ​​in Klaira. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Yarina’s symptoms of “syndrome” are quite small, just like Klaira’s.

Klaira or Yarina - which is better?

• the ability to use not only for contraception (treatment of edema, seborrhea and acne);
• a higher dosage of hormones means greater effectiveness.

• less likely to develop side effects due to the five-phase dosage cycle and reduced dosage;
• Can be used with caution by smoking women over 35 years of age.

It is believed that Yarina or Yarina Plus is best used by women in the age range from 20 to 35 years. During this period, the most effective contraception is required. Klaira or Yarina’s analogue Jess is more suitable for young girls or ladies over 35, as they contain fewer hormones.

What to choose?

Despite the fact that both drugs are contraceptives, the difference between them is quite significant. The main difference is the hormones and their amounts included in the drugs. Yarina has a higher dosage of hormones. The general indications for the drugs are the same, however, Yarina can be used to treat acne and swelling.

Qlaira has the following advantages:

1. There is a small likelihood of side effects due to the reduced dosage of hormones.
2. Can be used by smoking women over 35 years of age.
3. It has a beneficial effect on the endometrium, so it is often prescribed for endometriosis.

Yarina also has a number of positive qualities:

• Use is allowed to eliminate the symptoms of seborrhea and acne.
• Contains more hormones, which increases the effectiveness of the product.
• Drospirenone, which is part of the drug, has properties that prevent weight gain.
• It has a positive effect on lipid metabolism and increases the amount of “good cholesterol”.

Both drugs have many positive reviews. However, the composition of Yarina is difficult for the liver. Therefore, women with liver disease are not recommended to take this remedy. Qlaira is a modern drug and has a softer composition.

Thus, both drugs are effective for contraception and it is impossible to say which one is better. Only a doctor can make a specific choice of drug, based on the presence of contraindications in the woman and the general state of health. Therefore, it is not recommended to independently select and take oral contraceptives, since in the worst case, side effects may develop.

How to switch from Klaira to Yarina?

When the need arises to change one drug to another, the question often arises of how to do this correctly. The last few Qlaira tablets do not contain active ingredients, so many women often think that they can be skipped. The instructions recommend finishing the course of Qlaira completely, and the next day taking Yarina without a break.

oral contraceptives to protect against unwanted pregnancy . Pharmacological companies produce many contraceptives. The drugs Klayra and Yarina are often prescribed. Doctors often let the patient choose the drug on her own. Therefore, girls are faced with the question of which drug to choose. To figure out which drug is better, you should consider them in more detail.

Claira

The active ingredients are dienogest and estradiol valerate . Available in tablet form. Each pack contains several different doses of hormones.

Qlaira is a combined contraceptive. In almost all cases, it is well tolerated by patients. When taking pills, the ovulation process is inhibited and the viscosity of mucus increases. This prevents the trapped sperm from penetrating the egg and fertilizing it. In addition, the drug reduces the duration of the menstrual cycle. It also reduces the intensity of pain.

The bioavailability of estradiol is about 5% . Well absorbed from the gastrointestinal tract. The half-life is 1.5 hours . Excretion is carried out mainly by the kidneys, the rest by the intestines.

The bioavailability of dienogest is 90% . Absorbed from the gastrointestinal tract in almost unchanged quantities. It is excreted primarily by the kidneys. Final elimination occurs after 6 days.

The drug is used as a contraceptive to prevent unwanted pregnancy. Prolonged and painful menstruation is also an indication.

• Lactation.
• Venous thromboembolism.
• Blood diseases.
• Smoking, obesity and sedentary lifestyle.
• History of stroke.
• Changes in blood pressure.
• Women over 50 years old.
• Severe diabetes mellitus.
• Breast cancer.
• Liver diseases.
• Gallstones.

The tablets should be taken daily, 1 tablet per day at approximately the same time. Each package contains 26 active tablets and 2 inactive white tablets. Usually the dose begins with a second dark red or white tablet. Some women experience bleeding after taking the first pill. However, this does not require the intervention of specialists and the tablets must be taken continuously. If the drug has not been used before, the first tablet should be taken on the first day of menstruation.

Klaira or Yarina

According to the WHO (World Health Organization), COCs (combined oral contraceptives) can be used from puberty and the onset of menstruation (menarche), until perimenopause (the appearance of the first menopausal symptoms) for girls and women who have no contraindications to them. In this topic I would like to talk about the features of using COCs in different age groups.

Contraception in adolescents

has a number of features.
Unfortunately, 30%-60% of girls have experience of sexual activity before the age of 16. Often, pregnancy at this age is unwanted and ends in abortion. At the same time, adolescents are less tolerant of temporary side effects of COCs (nausea, engorgement of the mammary glands, etc.) and more often than adult women refuse contraception due to insufficient tolerability during the period of adaptation to the drug, i.e. in the first 3 months reception. As a rule, they are also poorly disciplined when it comes to punctuality associated with taking COCs at the same time every day. Features of the physiology of adolescence and the formation of the menstrual cycle are irregular, heavy or painful menstruation, dysfunctional uterine bleeding, the formation of functional ovarian cysts, skin problems - acne, seborrhea. From all of the above, the main rule for the use of COCs in adolescents follows: “light” COCs with the lowest doses of estrogens (microdosed) and metabolically neutral, with antiandrogenic activity, and are well tolerated, should be used. According to the dosage regimen for this age group, continuous use
(drugs in the package: 24 active tablets + 4 placebo), because
the absence of the need to space between packages is very convenient for teenagers. The latest innovation in oral contraception is metafolin contraceptives .
The addition of folate (folic acid) prevents anemia, depression, carbohydrate and fat metabolism disorders. The drugs of choice in adolescence are: Logest, Jess, Lindinet, Klaira, Novinet, Yarina.

Sexual relationships in adolescence are unstable: frequent changes of partners and spontaneous sex increase the risk of contracting sexually transmitted infections. Therefore, if you have several partners, in addition to taking COCs, you must also use a condom.

Contraception in early
and middle reproductive age (20-35 years)
must meet the requirements of reliability and rapid restoration of fertility (ability to conceive). At this age, a woman, as a rule, realizes her reproductive plans, but the rhythm of modern life forces her to “maneuver” between family and work. Therefore, in this age group the percentage of nulliparous women and late, delayed first pregnancies is increasing year by year. Young women, as a rule, have a satisfactory general level of health, but at the same time at this age they begin to manifest (appear and develop) gynecological dishormonal (uterine bleeding, premenstrual syndrome, ovarian cysts, mastopathy) and proliferative (uterine fibroids, endometriosis, hyperplastic endometrial processes) diseases. Young women are also demanding about their appearance: they are concerned about the condition of their skin and weight. Therefore, the drugs of choice for young women are low and micro-dose COCs with gestagens, which have a preventive antiproliferative effect on the uterus and appendages and a therapeutic (antiandrogenic) effect on the skin and hair. Optimal drugs at this age - Zhanin, Yarina. All drugs have a pronounced antiandrogenic effect, while the drug Zhanin has a more pronounced protective effect on the uterus and appendages, and the drugs Yarina have a decongestant effect.

Contraception in late reproductive age and perimenopause

It also has some features. As a rule, reproductive plans have already been implemented and, against the background of reduced hormonal ovarian function, fertility decreases. Unplanned pregnancy in women of this age group is a difficult test for the body, subject to numerous risks. The main requirements for contraception at this age are high reliability and minimal risk of metabolic disorders. When prescribing COCs to women of late reproductive age, a thorough examination is necessary not only by a gynecologist, but also by a therapist. The most optimal drug for this age group is Qlaira - the only COC with a five-phase dosing regimen and a low hormonal load, which maximally imitates the hormonal background of a normal menstrual cycle. So far, this is the only drug that uses estradiol valerate as an estrogen, an analogue of natural estrogen. Thanks to this, Klaira has the best safety profile.

No matter how old you are, remember that before you start taking hormonal medications, you need to consult with a good doctor who will examine and interview you before prescribing the most optimal medications for you.

Source: “Practical gynecology”, V. K. Likhachev

Yarina

The active substance is drospirenone and ethinyl estradiol . Available in tablet form. It is a contraceptive.

In women taking this drug, the duration of menstruation, as well as their abundance, decreases, and the severity of symptoms decreases. Due to this, the risk of developing iron deficiency anemia is reduced.

The maximum concentration of drospirenone in the blood is observed after 1.5 hours . Bioavailability is about 80%. The half-life is approximately 40 hours .

Ethinyl estradiol in maximum quantities is observed in the blood also after 1.5 hours. Bioavailability 45%. Excreted in urine and bile. Half-life is 24 hours.

The tablets are used to prevent pregnancy, as well as to relieve symptoms during menstruation. In addition, it eliminates acne, seborrhea and swelling associated with hormonal imbalance.

• Thrombosis and thromboembolism.
• Pancreatitis.
• Migraine with neurological symptoms.
• Diabetes.
• Kidney failure.
• Liver diseases.
• Hormone-dependent malignant neoplasms.
• Bleeding from the vagina of unknown origin.
• Lactation period.
• Pregnancy or suspicion of it.
• Allergic reaction to the components of the drug.

If any of the above disorders develops while taking the drug, it should be discontinued immediately.

Tablets are taken 1 piece per day at approximately the same time. After finishing the pack, a seven-day break is taken and “withdrawal bleeding” begins, usually on the 3-4th day. On the eighth day you need to start drinking a new pack. If the product is used for the first time, the first tablet should be taken on the first day of menstruation.

Composition and mechanism of action of the drug

The drug is presented in several tablets of different colors and with different compositions.

The dark yellow tablets contain 3 mg estradiol valerate; red - 2 mg of the same substance in combination with 2 mg of dienogest; light yellow - 2 mg estradiol valerate and 3 mg dienogest; dark red - 1 mg estradiol valerate. The common additional substance in all tablets is lactose monohydrate.

Also in the combination there are white placebo tablets, which contain no active substances, but only lactose.

Estradiol valerate

Estradiol valerate in this product acts as an estrogen, which is an alternative to 17 beta-estradiol (human hormone). It is this substance that, when entering a woman’s body, simulates the action of estrogen, which allows all systems to continue to work as usual. Those. this component compensates for the lack of these hormones, preventing the appearance of neuroses, irritability, hot flashes, pain and other symptoms of menopause. This substance differs from conventional synthetic hormones that are used in antimenopausal drugs, having greater metabolic stability.

Dienogest

The second active component, dienogest, is a progestogen and has minor antiestrogenic, estrogenic and androgenic properties, while at the same time exhibiting a significant antiandrogenic effect. It has a broad pharmacological effect, along with which it does not allow the first active substance to actively influence the endometrium, thereby reducing the risk of developing its neoplasms.