Nowadays there are many drugs on the pharmaceutical market aimed at preventing unwanted pregnancy. Janine or Silhouette are quite effective. These are combined contraceptives, which, in addition to the contraceptive effect, have other positive effects in the form of weakening the manifestation of premenstrual syndrome, reducing acne on the face and pain during menstruation.
Nowadays there are many drugs on the pharmaceutical market aimed at preventing unwanted pregnancy, including Janine and Silhouette.
Janine
The drug is considered a contraceptive belonging to the group of monophasic combined estrogen-progestogen drugs. Janine is based on the active ingredient ethinyl estradiol. In addition to it, the composition contains dienogest, lactose monohydrate, magnesium stearate, starch, gelatin and talc. The product is available in the form of tablets of 30 mcg + 2 mg, 21 or 63 pieces .
The effect of Janine is achieved thanks to the antiandroegnic activity of the main components. As a result of many studies, it was found that it affects not only protection against unwanted pregnancy, but also normalizes hormonal levels, improves the skin, relieving a woman of rashes, peeling, acne and post-acne. At the same time, the menstrual cycle normalizes after two to three months of regular use. There is evidence that the drug reduces the risk of ovarian and endometrial cancer.
The drug is prescribed to solve problems of unwanted pregnancy, and in some cases, gynecologists and endocrinologists prescribe it to treat diseases such as acne and rosacea.
The pills should be taken at the same time, never missing a pill . If missed, the contraceptive effect is reduced. Each new package starts after a week's break. During this time, the woman should experience bleeding, namely menstruation.
There is evidence that you can switch from this medication to another contraceptive without any problems. It can also be used after removal of the intrauterine device, vaginal ring and other contraceptives. However, in this case, the doctor may prescribe a slightly different dosage regimen, which is combined with the phases of the woman’s cycle.
Side effects often occur when taking contraceptives. These most often include the following:
- Dizziness.
- Nausea, vomiting.
- Menstrual irregularities in the first months of use.
- Bloody discharge during the period of adaptation of the body.
- Thrush.
- Uterine fibroids.
- Lipoma of the mammary glands.
- Increased or, conversely, lack of appetite.
- Dry mucous membranes.
- Stroke.
- Irritability, anger, depressive disorders.
- Heart rhythm disturbances.
- Phlebeurysm.
- Pain in the ovaries and mammary glands.
- Rash and other allergic reactions.
- Lack of menstruation for some time.
- Increase or decrease in body weight.
Among many studies conducted in different countries, it was found that most often side effects occur precisely at the beginning of taking the drug . Subsequently, the risk of their occurrence decreases, as the woman’s body adapts to new conditions.
There are many contraindications for which tablets cannot be used. These include:
- Thrombosis.
- Phlebeurysm.
- Angina pectoris, ischemia, other heart diseases.
- Diabetes.
- Vascular complications.
- Frequent headaches and migraines.
- Smoking and alcoholism.
- Diseases of the brain and blood vessels.
- Liver and kidney failure.
- Tumors of various origins.
- Bleeding.
- Pregnancy and lactation period.
- Children under 18 years of age.
- Sensitivity to components.
In the event of a sudden pregnancy, you cannot sharply reduce the dose of hormones received, so you should contact your doctor so that he can determine how to properly stop taking the drug in the future. Janine should not be taken during pregnancy.
Some doctors prescribe contraceptives for people under 18 years of age to treat acne and other skin problems caused by hormonal imbalances. In this case, taking Janine is possible, but under the supervision of a doctor.
The drug is available without a doctor's prescription, however, it must be remembered that combined oral contraceptives should be taken strictly under the supervision of a doctor and after passing the necessary tests.
Novinet
A cheaper analogue of the drug Zhanine, Novinet, is a combined contraceptive containing two hormones: desogestrel and ethinyl estradiol. This medication reduces the synthesis of gonadotropins and suppresses the ovulatory process. By increasing the viscosity of the mucus of the cervical canal, the active components make it difficult for the further movement of sperm. An analogue of estradiol, ethinyl estradiol, as well as desogestrel, help normalize lipid metabolism, reduce the abundance of menstrual flow, and improve the quality of the skin.
Novinet is not used for conditions such as:
- angina pectoris and severe hypertension;
- tendency to thromboembolism;
- the presence of stones in the gall bladder;
- liver pathologies and jaundice;
- tumor processes in the mammary glands;
- signs of pancreatitis with hypertriglyceridemia;
- pregnancy;
- smoking;
- breast-feeding.
Like other cheap analogues of the drug Zhanine, Novinet can cause nausea, weight gain, cephalgia, candidiasis, and depression. In case of an overdose of tablets, there is a high probability of vomiting and vaginal bleeding.
The price of Novinet, a cheap analogue of the drug Zhanine, averages 407 rubles.
Silhouette
The medicine Silhouette is prescribed by gynecologists to women to treat problems with menstrual irregularities, to restore hormonal levels, and also to solve contraceptive problems. The drug belongs to low-dose monophasic combined estrogen-progestogen contraceptives containing the main component ethinyl estradiol . The composition also contains dienogest, lactose monohydrate, starch, talc, potassium polyacryline, hypromellose 2910, and magnesium stearate.
Blisters are sold with 21 tablets each. There are also packs of three blisters on sale. The tablets themselves are white, odorless and tasteless. Easy to swallow with plenty of water.
The effectiveness of the product is obtained through a combination of two active ingredients - dienogest and ethinyl estradiol . They reduce the concentration of androgen in the blood, due to which women experience improved skin, a decrease in PMS symptoms, as well as other improvements in health.
Endocrinologists often prescribe this remedy specifically for the treatment of severe and moderate acne problems.
There are a number of contraindications for which contraceptives cannot be taken. These include:
- Venous insufficiency, or a tendency to its occurrence.
- Thrombosis and conditions preceding them.
- Heart attacks and other heart problems.
- Migraines and frequent headaches of unknown origin.
- The period when surgical intervention is expected.
- Pancreatitis.
- Liver and kidney failure.
- Pregnancy and lactation period.
- Lactose intolerance.
- Vague bleeding.
- Sensitivity to components.
Some women note the appearance of side effects, which usually occur at the very beginning of taking the drug, but later they disappear. These include:
- The occurrence of irregular bleeding or light spotting.
- Menstrual irregularities.
- Headache.
- Nausea, vomiting, diarrhea.
- Thrush.
- Anemia.
- Allergy.
- Loss of appetite - either increased or absent.
- Loss or gain of body weight.
- Changes in mood, depressive disorders, apathy, sudden mood swings.
- Dry mucous membranes.
- Increase or decrease in blood pressure.
- Rash.
- Pain and discomfort in the ovaries and mammary glands.
- Swelling of the limbs.
More serious complications and side effects of the drug include the appearance of various tumors, thrombosis, pancreatitis, liver and kidney dysfunction and other serious complications. In this case, the doctor stops taking this drug. However, such symptoms and pathologies occur extremely rarely.
Silhouette must be taken at the same time, without missing tablets . If missed, the absorption of the drug is impaired, which can lead to possible pregnancy. In this case, you need to take the pills according to the skip plan.
You can switch from Silhouette to other similar contraceptives and vice versa to Silhouette. However, it is necessary to strictly follow the instructions so as not to disrupt the cycle.
The mechanism of action of the drug Silhouette for endometriosis
The composition of one Silhouette tablet is represented by low doses of hormones:
- Dienogest – 2 mg.
- Ethinyl estradiol – 0.03 mg.
The mechanism of action of the drug is determined by the active substances included in its composition. Dienogest has a progestogenic effect, but does not have a pronounced androgenic, mineralocorticoid and glucocorticoid effect on the body. In other words, this substance helps regulate the excessive activity of estrogen, which is the cause of the development of endometriosis, but does not suppress a woman’s immunity. Dienogest does not interfere with the body's metabolic processes, so Silhouette can be taken for a long time (even several years).
As for ethinyl estradiol, this substance has high bioavailability when taken orally, allows cellular enzymes to transform into less active forms of estrogens and accelerates their breakdown.
The main effect of Silhouette on the body, which is important for the treatment of endometriosis:
- Reverse development, degeneration and subsequent atrophy of endometriosis foci in the uterus and beyond.
- Blocking the proliferation (possibility of germination) of new endometrioid heterotopias in tissues.
- Creating a “pseudo-pregnancy” effect, which leads to the achievement of amenorrhea, and subsequently to the cessation of hormonal activity in endometriotic lesions. Against the background of this condition, the ectopic endometrium undergoes regression, and new foci are not able to form.
- Termination of the local inflammatory reaction by blocking prostaglandins such as PG E2 and estrogen-like substances.
- Acceleration of local processes of decay of female hormones. Estradiol is transformed into inactive estrone. This, in turn, prevents the germination of new endometriosis lesions.
- Inhibition of angiogenesis processes, which prevents new blood vessels from forming around the foci of endometriosis and nourishing them.
- Suppression of ovulation and follicle formation, changes in the structure of the endometrium in the uterine cavity, decreased peristalsis of the fallopian tubes, thickening of mucus in the cervical canal - all these effects relate to the contraceptive properties of the drug. However, they were the basis for the treatment of endometriosis.
What do the drugs have in common?
Janine and Silhouette are contraceptives; they contain the same active substances - dienogest and ethinyl estradiol. These components have the necessary effect on reducing androgenic activity, as well as a contraceptive effect.
These and other tablets are in blisters of 21 pieces, which must be taken daily without skipping. Skips are made only between packages and in the case of taking Silhouette and Janine. They are accepted according to similar schemes.
The effect of both drugs is achieved through the action of the components of the composition. Doctors often prescribe these two medications not only for contraception, but also to treat many endocrine problems.
Janine or Silhouette: what to choose?
Nowadays there are many drugs on the pharmaceutical market aimed at preventing unwanted pregnancy. Janine or Silhouette are quite effective.
These are combined contraceptives, which, in addition to the contraceptive effect, have other positive effects in the form of weakening the manifestation of premenstrual syndrome, reducing acne on the face and pain during menstruation.
Nowadays there are many drugs on the pharmaceutical market aimed at preventing unwanted pregnancy, including Janine and Silhouette.
What's better
When choosing between one remedy or another, doctors most often rely on available indications and contraindications. In this case, they are absolutely identical in both the one and the second drug. Therefore, you can make a choice in favor of any of them. The content of the main components is identical.
Most often, women choose Janine because it has more reviews, and doctors often prescribe it, although it is much cheaper in price than Silhouette. However, if this drug is not on sale, then you can turn to the generic - Silhouette. Their composition is absolutely identical.
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